Correlation Monocyte Count, High Density Lipoprotein Cholesterol Levels and Monocyte High Density Lipoprotein Cholesterol Ratio with hsCRP Levels in Hypertension Patient [PDF]
Background: Hypertension is a condition which blood pressure in blood vessels increases chronically. Previous studies have shown that hypertension is associated with an inflammatory process involving innate and adaptive immune responses. Hypertension led
Rochman CHOLIQ +2 more
doaj +1 more source
Biological, clinical and population relevance of 95 loci for blood lipids. [PDF]
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides are among the most important risk factors for coronary artery disease (CAD) and are targets for therapeutic ...
Aulchenko, Yurii S +99 more
core
Replacement of dietary saturated fatty acids by trans fatty acids lowers serum HDL cholesterol and impairs endothelial function in healthy men and women [PDF]
We tested whether trans fatty acids and saturated fatty acids had different effects on flow-mediated vasodilation (FMD), a risk marker of coronary heart disease (CHD). Consumption of trans fatty acids is related to increased risk of CHD, probably through
Bots, M.L., Katan, M.B., Roos, N.M., de
core +2 more sources
Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]
Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui +3 more
core +2 more sources
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu +14 more
wiley +1 more source
BackgroundHigher concentrations of the apolipoprotein B (apoB) lipoproteins increase the risk of cardiovascular disease. However, whether the risk associated with apoB lipoproteins varies with age has not been well examined.
Allan D. Sniderman +6 more
doaj +1 more source
Effect of raw and heated flaxseed (Linum usitatissimum L.) on blood lipid profiles in rats. [PDF]
Flaxseed is a nutrient rich seed and lipid profiles improving effect of it has long been studied. Effect of heating as a part of food processing on its beneficial characteristics is not clarified in literature.
Ismail, Amin +2 more
core +1 more source
Is Too Much of a Good Thing a Good Thing? Extremely high high-density lipoprotein cholesterol with Coronary artery disease, Case report. [PDF]
Khalid Sawalha, Gilbert‐Roy Kamoga
openalex +1 more source
MicroRNAs and High-Density Lipoprotein Cholesterol Metabolism
MicroRNAs (miRNAs) are small non-protein-coding RNAs that negatively regulate gene expression. They bind to the 3'-untranslated region of specific mRNAs and inhibit translation or promote mRNA degradation. Dyslipidemia/hyperlipidemia is a well-accepted risk factor for the development of atherosclerosis.
Ono, Koh +5 more
openaire +3 more sources
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode +16 more
wiley +1 more source

