Results 41 to 50 of about 1,655,298 (265)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Comparative analysis of LDR and HDR intracavitary brachytherapy in cervical cancer: the critical role of overall treatment time — a decade of experience

Reports of Practical Oncology and Radiotherapy
BACKGROUND: This study compares low dose rate (LDR) and high dose rate (HDR) intracavitary brachytherapy (ICBT) in the treatment of cervical cancer treated at a tertiary care cancer centre in North India.
Purnima Thakur, Kaalindi Singh, Vineet Lakhanpal, Manish Gupta, Lalit C. Kant, Parul Sharma   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

High-dose-rate brachytherapy as monotherapy for prostate cancer

Brachytherapy, 2014
To review and analyze the published data on high-dose-rate brachytherapy as monotherapy in the treatment of prostate cancer.A literature search and a systematic review of the high-dose-rate (HDR) brachytherapy (monotherapy) prostate literature were performed on PubMed using "high-dose-rate, brachytherapy, prostate, monotherapy" as search terms.
Demanes, D. Jeffrey, Ghilezan, Michel I.
openaire   +4 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Improving prostate brachytherapy outcomes through MRI-Assisted dominant lesion dose painting

BMC Urology
Background The aim of this study was to assess the feasibility of using magnetic resonance (MR) images to implement a dose painting (DP) approach in prostate high-dose-rate brachytherapy.
Faranak Rahmani, Mohammad Javad Tahmasebi Birgani, Fatemeh Mohammadian, Maryam Feli, Seyed Masoud Rezaeijo   +4 more
doaj   +1 more source

High-dose-rate brachytherapy in the treatment of skin Kaposi sarcoma

Journal of Contemporary Brachytherapy, 2017
Purpose : The aim of the study is to review our experience in treatment of Kaposi sarcoma (KS) lesions with high-dose-rate (HDR) brachytherapy. Material and methods : We present five new KS lesions (three patients) that were treated in our hospital ...
María Ángeles González Ruiz, Juan Quirós Rivero, Julia Luisa Muñoz García, Joaquín José Cabrera Rodríguez, Yesika Ríos Kavadoy, María Francisca Ropero Carmona, Almudena Corbacho Campos, Fernando García Urra, María Cristina Cruz Muñoz, Amanda Ruiz Herrero, Pedro Almendral Manzano   +10 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Perioperative interstitial high-dose-rate brachytherapy for keloids scar

Journal of Contemporary Brachytherapy, 2022
Victoria Vera Barragán, Ana Isabel Alonso García, José Fernández García, Marta De Juan Marín, Johanna del Carmen Peña Vivas, Germán Juan Rijo   +5 more
doaj   +1 more source