Early Toxicities After High Dose Rate Proton Therapy in Cancer Treatments
BackgroundThe conventional dose rate of radiation therapy is 0.01–0.05 Gy per second. According to preclinical studies, an increased dose rate may offer similar anti-tumoral effect while dramatically improving normal tissue protection. This study aims at
Jérôme Doyen +17 more
doaj +1 more source
Brachytherapy boost in anal canal cancer – A GEC ESTRO PDR task force meta-analysis
Purpose: A meta-analysis is presented comparing clinical outcomes and toxicities between high dose rate (HDR) and pulsed dose rate (PDR) brachytherapy (BT) for anal cancer.
Pierre Annede +7 more
doaj +1 more source
Factors modifying the response of large animals to low-intensity radiation exposure [PDF]
In assessing the biological response to space radiation, two of the most important modifying factors are dose protraction and dose distribution to the body.
Page, N. P., Still, E. T.
core +1 more source
Improving plan quality and consistency by standardization of dose constraints in prostate cancer patients treated with CyberKnife. [PDF]
Treatment plans for prostate cancer patients undergoing stereotactic body radiation therapy (SBRT) are often challenging due to the proximity of organs at risk.
Carrara, Mauro +10 more
core +2 more sources
Nerve tolerance to high-dose-rate brachytherapy in patients with soft tissue sarcoma: a retrospective study [PDF]
Background Brachytherapy, interstitial tumor bed irradiation, following conservative surgery has been shown to provide excellent local control and limb preservation in patients with soft tissue sarcomas (STS), whereas little is known about the tolerance ...
Tadahiko Kubo +27 more
core +2 more sources
The influence of beam parameters on FLASH effect
Ultra-high dose rate radiotherapy (FLASH-RT) is typically defined as an external beam radiotherapy that utilizes a dose rate of 40 Gy/s or higher, compared with conventional dose rate radiotherapy (≤0.1 Gy/s).
Binwei Lin +15 more
doaj +1 more source
Equivalent titanium dioxide nanoparticle deposition by intratracheal instillation and whole body inhalation: the effect of dose rate on acute respiratory tract inflammation [PDF]
BACKGROUND: The increased production of nanomaterials has caused a corresponding increase in concern about human exposures in consumer and occupational settings.
Alison Elder +6 more
core +1 more source
Thermoluminescence of zircon: a kinetic model [PDF]
The mineral zircon, ZrSiO4, belongs to a class of promising materials for geochronometry by means of thermoluminescence (TL) dating. The development of a reliable and reproducible method for TL dating with zircon requires detailed knowledge of the ...
A A Turkin +31 more
core +2 more sources
A systematic review of treating recurrent head and neck cancer: a reintroduction of brachytherapy with or without surgery. [PDF]
Purpose: To review brachytherapy use in recurrent head and neck carcinoma (RHNC) with focus on its efficacy and complication rates. Material and methods: A literature search of PubMed, Ovid, Google Scholar, and Scopus was conducted from 1990 to 2017 ...
Bar-Ad, Voichita +10 more
core +1 more source
Monte Carlo study of radiation dose enhancement by gadolinium in megavoltage and high dose rate radiotherapy. [PDF]
MRI is often used in tumor localization for radiotherapy treatment planning, with gadolinium (Gd)-containing materials often introduced as a contrast agent. Motexafin gadolinium is a novel radiosensitizer currently being studied in clinical trials.
Daniel G Zhang +4 more
doaj +1 more source

