Results 51 to 60 of about 65,655 (333)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Developing novel high-Si 12 % Cr reduced-activation ferritic/martensitic cladding alloys via the cluster-formula approach and CALPHAD method

Materials & Design
The corrosion-resistance in lead–bismuth eutectic (LBE) coolant at elevated temperatures of traditional reduced-activation ferritic/martensitic (RAFM) steels could not meet the requirements for the application of fuel claddings.
Sen Ge, Ben Niu, Zhenhua Wang, Qing Wang, Qianfu Pan, Chaohong Liu, Chuang Dong, Peter K. Liaw   +7 more
doaj   +1 more source

Mechanical Properties and Microstructure of a NiCrFeCoMn High-Entropy Alloy Deformed at High Strain Rates

Entropy, 2018
The equiatomic NiCrFeCoMn high-entropy alloy prepared by arc melting has a single crystallographic structure. Mechanical properties and microstructure of the NiCrFeCoMn high-entropy alloy deformed at high strain rates (900 s−1 to 4600 s−1 ...
Bingfeng Wang, Xianrui Yao, Chu Wang, Xiaoyong Zhang, Xiaoxia Huang   +4 more
doaj   +1 more source

Positive Vibrational Entropy of Chemical Ordering in FeV [PDF]

, 2011
Inelastic neutron scattering and nuclear resonant inelastic x-ray scattering were used to measure phonon spectra of FeV as a B2 ordered compound and as a bcc solid solution.
Abernathy, D. L., Chow, Paul, Delaire, O., Fultz, B., Li, Chen W., Lucas, M. S., Mauger, L., Muñoz, J. A., Sheets, A. O., Stone, M. B., Winterrose, M. L., Xiao, Yuming   +11 more
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Surface Nanostructuring of Copper Using Fluoride and Chloride

ChemElectroChem
Copper is an active electrocatalyst for various energy conversion reactions, but its performance depends on the structure of the active surface sites. In this work, we propose a simple strategy to tailor both the roughness and the active site's geometry ...
Vicente Pascual‐Llorens, Albert Serra Ramos, Pedro Mazaira‐Couce, María Escudero‐Escribano, Paula Sebastián‐Pascual   +4 more
doaj   +1 more source

Computational high entropy alloy design [PDF]

MATEC Web of Conferences
Materials scientists are developing new materials to meet increasing demands by employing a systematic approach linking material performance to composition, processing, and microstructure.
Simelane Khombisile, Becker Thorsten Hermann   +1 more
doaj   +1 more source

A cost-effective eutectic high entropy alloy with an excellent strength–ductility combination designed by VEC criterion

Journal of Materials Research and Technology, 2022
Due to the excellent combination of strength and ductility, eutectic high entropy alloys (EHEAs) are of great interests to the researchers. Here, a cobalt free cost-effective eutectic high entropy alloy was designed by VEC criterion.
Hao Wu, Jun Xie, Huaiyu Yang, Delong Shu, Guichen Hou, Jinguo Li, Yizhou Zhou, Xiaofeng Sun   +7 more
doaj   +1 more source

Magnetic and vibrational properties of high-entropy alloys [PDF]

, 2011
The magnetic properties of high-entropy alloys based on equimolar FeCoCrNi were investigated using vibrating sample magnetometry to determine their usefulness in high-temperature magnetic applications.
Horwath, J., Lucas, M. S., Mauger, L., Muñoz, J. A., Semiatin, S. L., Sheets, A. O., Turgut, Z., Xiao, Yuming   +7 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source