Results 51 to 60 of about 49,275 (283)

The formation of sigma phase in the CoCrFeNi high-entropy alloys

Materials Research Express, 2021
The as-cast CoCrFeNi high-entropy alloys show simple FCC structure and outstanding deformation ability at room temperature. Respectively, after 50% of deforming at room temperature and annealing at intermediate temperature range of 600 °C–800 °C for 2 h,
X J Wang, M Xu, N Liu, L X Liu
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Research progress in composition design, microstructure and properties of refractory high entropy alloys

Journal of Aeronautical Materials, 2022
High entropy alloy is defined as an alloy containing four or more main elements. The atomic fraction of the main elements is greater than 5% and not more than 35%, which has excellent properties such as high strength, high wear resistance and high ...
WU Junxia, LI Peiyou, DONG Hongfeng, LIU Yaling, ZHANG Wei, WANG Lin, WANG Yongshan   +6 more
doaj   +1 more source

Entropy change at the martensitic transformation in ferromagnetic shape memory alloys Ni_{2+x}Mn_{1-x}Ga

, 2003
The entropy change $\Delta S$ between the high-temperature cubic phase and the low-temperature tetragonally-based martensitic phase of Ni$_{2+x}$Mn$_{1-x}$Ga ($x = 0 - 0.20$) alloys was studied.
K. Oikawa, Khovailo V. V., Khovailo V. V., Matsumoto M., Obradó E., Pelegrina J. L., T. Abe, T. Takagi, V. V. Khovailo   +8 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Research Progress and Prospect of High-Entropy Alloy Materials

中国工程科学, 2023
With the rapid development of world’s technological level and the urgent demand of national economic construction for high-performance alloy materials, traditional single-component alloys gradually fail to satisfy the increasing service requirements ...
Li Tianxin, Wang Shudao, Lu Yiping, Cao Zhiqiang , Wang Tongmin, Li Tingju   +5 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Electron-phonon interactions and high-temperature thermodynamics of vanadium and its alloys [PDF]

, 2008
Inelastic neutron scattering was used to measure the phonon densities of states (DOSs) for pure V and solid solutions of V with 6 to 7at% of Co, Nb, and Pt, at temperatures from 10 K to 1323 K.
Delaire, O., Fultz, B., Kresch, M., Lin, J. Y. Y., Lucas, M. S., Muñoz, J. A.   +5 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Magnesium Containing High Entropy Alloys

, 2022
High Entropy alloys (HEAs) or Complex Concentrated Alloys (CCAs) or Multi-Principal Element Alloys (MPEAs) is a matter of interest to material scientists for the last two decades due to the excellent mechanical properties, oxidation and corrosion resistant behaviors. One of the major drawbacks of HEAs is their high density.
Prince, Sharma,, Nushrat, Naushin,, Sahil, Rohila,, Abhishek, Tiwari,   +3 more
openaire   +3 more sources