Results 41 to 50 of about 57,713 (310)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
High frequency link Uninterruptible Power Supply (UPS) system [PDF]
, 2013 This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.The main aim of this thesis is to propose, design, simulate and build a new UPS system which can be used for compact applications.
Rasool, Emad Abdulrazzaq
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Transformers in High-Frequency Trading
Journal of Physics: Conference SeriesAbstract Transformer is a deep learning model that, having an innovative performance in many tasks, has uniquely and significantly modified all the cast of mind of the AI scientific community. In this paper, we introduce a Transformer model that is applied to 1-minute timescale in the EURUSD and GBPUSD instruments of forex trading.
Konstantinos T. Kantoutsis +2 more
openaire +1 more source
Simulation of dielectric frequency response of transformer insulation system [PDF]
, 2013 Frequency domain spectroscopy has been widely used to monitor the condition of insulation system in power transformers. For a core type of transformer, a simplified XY model of a duct has been developed which allows one to examine the contribution from ...
Yu, Guo, Chen, George
core
Pre-breakdown Characteristics of Contaminated Power Transformer Oil [PDF]
, 2007 In this paper we have studied pre-breakdown characteristics of transformer oil in the presence of different levels of contamination. The contaminant is fibrous dust from pressboard insulation used for high voltage transformers.
Zuber, H M +3 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Journal of Water and Climate Change, 2023 Accurate runoff prediction is of great significance for flood prevention and mitigation, agricultural irrigation, and reservoir scheduling in watersheds. To address the strong non-linear and non-stationary characteristics of runoff series, a hybrid model
Shaolei Guo +3 more
doaj +1 more source
High frequency inverter-transformer-cycloconverter system for DC to AC (3-phase) power conversion [PDF]
, 1991 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis is concerned with a 3-phase multistage high frequency link DC to AC power conversion with a novel inverter-cycloconverter circuitry.
Karamat, Asghar
core