Results 81 to 90 of about 13,357 (265)

Loss analysis and thermal structure design of large-capacity medium-frequency transformers with ultra-thin grain-oriented silicon steel cores

Zhejiang dianli
Ultra-thin grain-oriented silicon steel features low medium-frequency loss and high magnetic induction， giving it strong application potential in large-capacity medium-frequency transformers.
LIN Jiajun, GAO Hao, PAN Ming, LI Bonian, GU Xiaohu, ZHANG Zhili   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Models for a Fast Computation of Internal Overvoltages in Medium-Frequency Transformers

IEEE Open Journal of Power Electronics
The fast switching of wide-bandgap (WBG) devices and the resulting harmonics in the switching waveforms can cause significant overvoltages in medium frequency transformers (MFTs).
Bastian Korthauer, Jurgen Biela
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Ghost-Free HDR Imaging in Dynamic Scenes via High–Low-Frequency Decomposition

Sensors
Generating high-quality high-dynamic-range (HDR) images in dynamic scenes remains a challenging task. Recently, Transformers have been introduced into HDR imaging and have demonstrated superior performance over traditional convolutional neural networks ...
Xiang Zhang, Genggeng Chen, Fan Zhang, Yongzhong Zhang   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Multi‐Physics Distribution Characteristics of Modules for Large‐Capacity HVDC Transformer Under Intermediate Frequency Conditions

IET Electric Power Applications
Large‐capacity high voltage direct current (HVDC) transformers are the core equipment of the future power system. The design and operation of these transformers involve the interaction of multiple physical fields.
Jianwen Nie, Jiachen Gao, Tongshu Ding, Tingxiu Jiang, Zhikang Shuai   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Selection of an Optimal Frequency for Offshore Wind Farms

Energies
Offshore wind power has attracted significant attention due to its high potential, capability for large-scale farms, and high capacity factor. However, it faces high investment costs and issues with subsea power transmission. Conventional high-voltage AC
Byeonghyeon An, Junsoo Che, Taehun Kim, Taesik Park   +3 more
doaj   +1 more source