Results 81 to 90 of about 11,295 (242)

The Australian Penile Cancer Clinical Registry: a comprehensive national approach to data collection

open access: yesBJU International, EarlyView.
Background Penile cancer is a rare malignancy, with an Australian incidence of 0.6 in 100 000 men, with a wide range of clinical presentations, from localised, curable tumours to aggressive forms with high morbidity and mortality. Epidemiological data and management guidelines for penile cancer in Australia are limited.
Henry Y.C. Pan   +11 more
wiley   +1 more source

Use of parallel fluorescent confocal microscopy for detection of prostatic adenocarcinoma

open access: yesBJU International, EarlyView.
Objective To provide a histological catalogue and defined criteria for the diagnosis of prostatic adenocarcinoma and its variants using the fluorescent confocal microscope (FCM) platform. Methods A total of 22 radical prostatectomy specimens were serially sectioned and scanned with the FCM.
Kevin Clare   +13 more
wiley   +1 more source

Evaluation of immunoexpression and MDR1 promoter methylation levels in prostatic tissue samples [PDF]

open access: yes, 2008
Os objectivos deste estudo foram: (1) Determinar os níveis de metilação do promotor do MDR1 em tecido prostático com adenocarcinoma (CaP), neoplasia intraepitelial prostática de alto grau (HGPIN), hiperplasia benigna (BPH) e tecido morfologicamente ...
Costa, Vera L.   +5 more
core  

PSA and anthropometric measurements among Amazon Indians: an evaluation of the Parkatejê community [PDF]

open access: yes, 2003
OBJECTIVE: PSA (prostate-specific antigen) screening for early detection of prostate cancer in a native community is of great epidemiological importance.
Arruda, Homero Oliveira de [UNIFESP]   +3 more
core   +1 more source

Diagnosis of penile cancer with ex vivo fluorescence confocal microscopy using the Histolog® Scanner

open access: yesBJU International, EarlyView.
Objectives To evaluate the feasibility and diagnostic performance of ex vivo fluorescence confocal microscopy (FCM) using the Histolog® Scanner (SamanTree Medical SA, Lausanne, Switzerland) for the assessment of penile cancer (PeCa) specimens, and to compare FCM‐based diagnoses with standard formalin‐fixed, paraffin‐embedded (FFPE) histopathology ...
Xiaohu Zhang   +8 more
wiley   +1 more source

High Grade Prostatic Intraepithelial Neoplasia and the Risk of Prostate Cancer

open access: yesOpen Journal of Urology, 2018
Introduction: High Grade Prostatic Intraepithelial Neoplasia (HGPIN) was originally thought to be a cancer precursor, but subsequent data has questioned its prognostic significance. We analyzed a large cohort of men diagnosed with HGPIN for subsequent occurrence of prostate cancer.
Gregory P. Swanson   +4 more
openaire   +2 more sources

Building a Robust Investigator‐Initiated Platform: The I‐CARE Experience

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1537-1546, June 2026.
Investigator‐initiated studies that include information collected by patients are rising, but limited data is available on patient and investigator experience in this setting. The I‐CARE cohort included patients with inflammatory bowel disease (IBD) monthly collecting clinical information in 15 countries for up to 6 years.
Julien Kirchgesner   +906 more
wiley   +1 more source

Role of IAPs in prostate cancer progression: immunohistochemical study in normal and pathological (benign hyperplastic, prostatic intraepithelial neoplasia and cancer) human prostate

open access: yesBMC Cancer, 2010
Background In this study was investigate IAPs in normal human prostate (NP), benign prostatic hyperplasia (BPH), prostatic intraepithelial neoplasia (PIN) and prostatic carcinoma (PC), and their involvement in apoptosis/proliferation via NF-kB (TNF-α, IL-
Olmedilla Gabriel   +10 more
doaj   +1 more source

Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate. [PDF]

open access: yes, 2019
Recent genome analysis of human prostate cancers demonstrated that both AR gene amplification and TP53 mutation are among the most frequently observed alterations in advanced prostate cancer. However, the biological role of these dual genetic alterations
Aldahl, Joseph   +14 more
core  

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

open access: yeseFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie   +5 more
wiley   +1 more source

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