Results 261 to 270 of about 422,572 (333)

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Soft Bioelectronic Interfaces for Continuous Peripheral Neural Signal Recording and Robust Cross‐Subject Decoding

Advanced Science, EarlyView.
A soft poly (3,4‐ethylenedioxythiophene):poly (styrenesulfonate)‐based electrode enables continuous, high‐quality recording of peripheral nerve activity. A neural network model integrating handcrafted and convolutional neural network‐based features decodes whisker movements with strong generalization, offering insights into peripheral nerve function ...
Liangpeng Chen, Yang Liu, Yewei Huang, Ziyang Li, Chao Zhang, Jun Tang, Xueyuan Ling, Bowen Cao, Baowang Li, Yuan Zhang, Wenjianlong Zhou, Qin Xu, Shunchang Ma, Xiudong Guan, Dan Xiao, Jingyao Geng, Yutong Zhao, Guolin Li, Yi‐xuan Wang, Wang Jia, Yuanwen Jiang, Milin Zhang, Deling Li   +22 more
wiley   +1 more source

Enhancing psychological health and cognitive inhibition in college students: insights from mindfulness training and high-intensity interval training. [PDF]

Front Psychol
Bao Y, Sun J, Zhang X.
europepmc   +1 more source

Impact of long-term high-intensity interval and moderate-intensity continuous training on subclinical inflammation in overweight/obese adults

, 2016
José Gerosa-Neto, Barbara Moura Antunes, Eduardo Zapaterra Campos, Jhennyfer Aline Lima Rodrigues, Gustavo Duarte Ferrari, José Cesar Rosa Neto, Carlos Roberto Bueno Júnior, Fábio Santos Lira   +7 more
openalex   +1 more source

Multimodal Investigation of Angiogenesis and Its Prevention by Small Compounds in a Zebrafish Cancer Model

Advanced Science, EarlyView.
A combined optical coherence tomography angiography and fluorescence imaging approach assesses tumor angiogenesis and drug effects in a novel zebrafish cancer model. By analyzing 3D vasculature data, the two imaging methods complement each other to quantify blood flow, vessel structure, and drug efficacy.
Marco Andreana, Ryan Sentosa, Caterina Sturtzel, Martin Pfister, René Werkmeister, Anna Schmitt, David Traver, Rainer Leitgeb, Wolfgang Drexler, Martin Distel, Angelika Unterhuber   +10 more
wiley   +1 more source

Is High-Intensity Interval Training an Option for Post-Kidney Transplant Physical Rehabilitation Programmes? A Scoping Review. [PDF]

J Multidiscip Healthc
Lovatto V, Sousa BDS, Marães VRFDS.
europepmc   +1 more source

Effect of Novel, School-Based High-Intensity Interval Training (HIT) on Cardiometabolic Health in Adolescents: Project FFAB (Fun Fast Activity Blasts) - An Exploratory Controlled Before-And-After Trial

, 2016
Kathryn L. Weston, Liane B. Azevedo, Susan Bock, Matthew Weston, Keith George, Alan M. Batterham   +5 more
openalex   +2 more sources

Mesenchymal Stromal Cell Secretome and Its Key Bioactive Metabolites Induce Long‐Term Neuroprotection After Traumatic Brain Injury in Mice

Advanced Science, EarlyView.
Pischiutta F and coworkers identify prostaglandins and kynurenine as key mediators of the mesenchymal stromal cells‐derived secretome's neuroprotective effects. A synthetic cocktail composed of these factors promotes long‐term functional recovery, reduces brain structural damage, and modulates neuroinflammation after traumatic brain injury, supporting ...
Francesca Pischiutta, Francesca Tribuzio, Marta Magatti, Giulia De Simone, Federico Moro, Giovanni Nattino, Fabiola Signorini, Luther Loose, Enrico Caruso, Costanza Bertani, Edoardo Mazzone, Rosaria Pascente, Edoardo Micotti, Antonietta Rosa Silini, Fabrizio Ortolano, Maria Chiara Trolese, Marco Bolis, Luca Guarrera, Martina Bruna Violatto, Paolo Bigini, Cristina Banfi, Roberta Pastorelli, Ornella Parolini, Laura Brunelli, Elisa R Zanier   +24 more
wiley   +1 more source

Deep phenotyping of patients with MASLD upon high-intensity interval training. [PDF]

JHEP Rep
Houttu V, Boulund U, Troelstra M, Csader S, Stols-Gonçalves D, Mak AL, Dijk AV, Bouts J, Winkelmeijer M, Verdoes X, van den Berg-Faay S, Lek D, Ronteltap T, de Haan F, Jorstad H, Männistö V, Savonen K, Pentikäinen H, Hanhineva K, Babu AF, Panagiotou G, van Delden O, Verheij J, Doukas M, Nederveen A, Schwab U, Grefhorst A, Nieuwdorp M, Holleboom AG.   +28 more
europepmc   +1 more source