Results 51 to 60 of about 1,093,472 (338)

isQ: An Integrated Software Stack for Quantum Programming

open access: yesIEEE Transactions on Quantum Engineering, 2023
We introduce isQ, a new software stack for quantum programming in an imperative programming language, also named isQ. The aim of isQ is to make programmers write quantum programs as conveniently as possible.
Jingzhe Guo   +8 more
doaj   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

Quasar: A Programming Framework for Rapid Prototyping [PDF]

open access: yes, 2016
We present a new programming framework, Quasar, which facilitates GPU programming. Our high-level programming language relieves the developer of all implementation details such that he can focus on the algorithm and the required accuracy.
De Vylder, Jonas, Goossens, Bart
core   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Advancing Software Development for a Multiprocessor System-on-Chip [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2007
A low-level language is the right tool to develop applications for some embedded systems. Notwithstanding, a high-level language provides a proper environment to develop the programming tools.
Stephen Bique
doaj  

Creating Prototype Virus - Destroying Files and Texts on Any Computer

open access: yesPrizren Social Science Journal, 2019
When we study how viruses work and prevent them, we've developed a very simple application where we can see a prototype of a virus and virus function, as well as neutralizing a file if we want to break it down its structure at the level of the bits ...
Naim BAFTIU, Samedin KRABAJ
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Teaching Programming Principles through a Game Engine

open access: yesCLEI Electronic Journal, 2010
Teaching fundamental programming to freshmen is a hard task to be performed, given the high level of abstraction and logical reasoning that are required for these students to develop in a very early stage of their course. This paper presents a discussion
Cristiane Camilo Hernandez   +6 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

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