Results 71 to 80 of about 598,758 (344)

Sprego Programming

open access: yesSpreadsheets in Education, 2014
Spreadsheet management is a border-land between office applications and programming, however, it is rather communicated that spreadsheet is nothing more than an easily handled fun piece.
Maria Csernoch, Piroska Biró
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Sprego Programming

open access: yesSpreadsheets in Education, 2015
Spreadsheet management is a border-land between office applications and programming, however, it is rather communicated that spreadsheet is nothing more than an easily handled fun piece.
Maria Csernoch, Piroska Biró
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Meaning and Reference in Programming Languages

open access: yesPhilosophies
This paper provides an analysis of the meaning–reference problem, as traditionally advanced in the philosophy of language, for imperative programming languages.
Nicola Angius
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

CONSIDERATIONS ON OBJECT-ORIENTED PROGRAMMING ENVIRONMENT AUTOCAD DRAWINGS

open access: yesJournal of Industrial Design and Engineering Graphics, 2015
In recent years, Low Cost CAD systems are widespread in the technical world. Currently, the highest-rated CAD system is AutoCAD due to the fact that in association with AutoLISP programming language covered a broad range of production needs.
PINTILIE Alexandru, AVRAM Elena Rita
doaj  

Domain Specific Abstractions for the Development of Fast-by-Construction Dataflow Codes on FPGAs

open access: yesChips
FPGAs are popular in many fields but have yet to gain wide acceptance for accelerating HPC codes. A major cause is that whilst the growth of High-Level Synthesis (HLS), enabling the use of C or C++, has increased accessibility, without widespread ...
Nick Brown
doaj   +1 more source

Acute: high-level programming language design for distributed computation

open access: yes, 2005
Existing languages provide good support for typeful programming of standalone programs. In a distributed system, however, there may be interaction between multiple instances of many distinct programs, sharing some (but not necessarily all) of their ...
Sewell, Peter   +6 more
core  

High-Confidence, Modular Compiler Development in a Formal Environment [PDF]

open access: yes, 2005
We present a methodology for realistic compiler development in an existing formal methods framework. Program transformations and analyses are implemented as term rewrites and inference rules, and automated proof search techniques are used to drive the ...
Gray, Nathaniel Asoka
core   +1 more source

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