Results 51 to 60 of about 749,786 (298)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
ORTHORECTIFICATION BY USING GPGPU METHOD [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2012 Thanks to the nature of the graphics processing, the newly released products offer highly parallel processing units with high-memory bandwidth and computational power of more than teraflops per second.
H. Sahin, S. Kulur
doaj +1 more source
HIGH LEVEL LANGUAGE STRUCTURES FOR DISTRIBUTED REAL-TIME PROGRAMMING
IFAC Proceedings Volumes, 1979 Abstract In the paper software tools are described which allow structured concurrent programming of loosely coupled distributed systems with common memory. Sequential program parts and all structures serving for control, communication and synchronization of these parts are strictly separated. The PARC (= par allel c onstruct) concept, derived from
W.-M. Dehnert, V.H. Haase
openaire +1 more source
Rust-Bio - a fast and safe bioinformatics library
, 2015 We present Rust-Bio, the first general purpose bioinformatics library for the innovative Rust programming language. Rust-Bio leverages the unique combination of speed, memory safety and high-level syntax offered by Rust to provide a fast and safe set of ...
Köster, Johannes
core +2 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Is Julia ready to be adopted by HEP? [PDF]
EPJ Web of ConferencesThe Julia programming language was created 10 years ago and is now a mature and stable language with a large ecosystem including more than 8,000 third-party packages.
Gál Tamás +12 more
doaj +1 more source
Julia: A Fresh Approach to Numerical Computing [PDF]
, 2014 Bridging cultures that have often been distant, Julia combines expertise from the diverse fields of computer science and computational science to create a new approach to numerical computing. Julia is designed to be easy and fast. Julia questions notions
Bezanson, Jeff +3 more
core +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Spreadsheets in Education, 2014 Spreadsheet management is a border-land between office applications and programming, however, it is rather communicated that spreadsheet is nothing more than an easily handled fun piece.
Maria Csernoch, Piroska Biró
doaj
Object oriented execution model (OOM) [PDF]
, 2011 This paper considers implementing the Object Oriented Programming Model directly in the hardware to serve as a base to exploit object-level parallelism, speculation and heterogeneous computing.
Cristal Kestelman, Adrián +5 more
core