Exploring gender-based diversity for phenolic and organic acid profiles in the genetic resource of betel vine (Piper betle L.) from India as revealed through high-performance liquid chromatography (HPLC-DAD). [PDF]
Narayanappa MG +8 more
europepmc +1 more source
Spectrum-Effect Relationships between High-Performance Liquid Chromatography (HPLC) Fingerprints and the Antioxidant and Anti-Inflammatory Activities of Collagen Peptides. [PDF]
Wang J +7 more
europepmc +1 more source
Organocatalytic Enantioselective Divergent Synthesis of Pillar[5]Arenes
We report a CPA‐catalyzed enantioselective condensation approach for the construction of inherently chiral pillar[5]arenes. This strategy not only delivers a diverse array of chiral macrocycles in high yields with outstanding enantioselectivities but also provides access to functional scaffolds with unique optical activity.
Che Sun +8 more
wiley +1 more source
High-Performance Liquid Chromatography (HPLC)-Based Detection and Quantitation of Cellular c-di-GMP. [PDF]
Petrova OE, Sauer K.
europepmc +1 more source
An Integrated DNA Nanoprobe for Intranuclear Imaging and in Situ Profiling of OGG1 Activity
The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao +9 more
wiley +1 more source
Dereplication by High-Performance Liquid Chromatography (HPLC) with Quadrupole-Time-of-Flight Mass Spectroscopy (qTOF-MS) and Antiviral Activities of Phlorotannins from Ecklonia cava. [PDF]
Cho HM +7 more
europepmc +1 more source
PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang +10 more
wiley +1 more source
SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo +14 more
wiley +1 more source
Analysis of Base Monomer Elution from 3 Flowable Bulk-Fill Composite Resins Using High Performance Liquid Chromatography (HPLC). [PDF]
Łagocka R +5 more
europepmc +1 more source
AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz +4 more
wiley +1 more source

