Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao +12 more
wiley +1 more source
High-Performance Liquid Chromatography (HPLC)-Based Detection and Quantitation of Cellular c-di-GMP. [PDF]
Petrova OE, Sauer K.
europepmc +1 more source
Non‐ideal redox electrolytes still govern the Nernstian behavior of electrode potentials in aqueous organic redox flow batteries under operation. We utilized this effect to analytically predict two scenarios of battery performance degradation. ABSTRACT Aqueous organic redox flow batteries (AORFBs) enhance the sustainability of battery energy storage ...
Faudillah Alhumairah +9 more
wiley +1 more source
Dereplication by High-Performance Liquid Chromatography (HPLC) with Quadrupole-Time-of-Flight Mass Spectroscopy (qTOF-MS) and Antiviral Activities of Phlorotannins from Ecklonia cava. [PDF]
Cho HM +7 more
europepmc +1 more source
This work presents a rational electrode design for electrochemical CO2 reduction, employing Ag nanowire networks as both current collectors and tandem catalysts. The Ag nanowires are deposited onto the catalyst layer, forming a stacked PTFE/catalyst/Ag nanowires configuration.
Jonghyeok Park +3 more
wiley +1 more source
Analysis of Base Monomer Elution from 3 Flowable Bulk-Fill Composite Resins Using High Performance Liquid Chromatography (HPLC). [PDF]
Łagocka R +5 more
europepmc +1 more source
Engineering a Virus‐Derived X Family DNA Polymerase FvPolX for de novo DNA Synthesis
In this study, a Faustovirus‐derived polymerase (FvPolX) is engineered based on structural and sequence analysis of PolX enzymes. The optimal mutants demonstrate substantially enhanced catalytic activity toward dNTPs and 3′‐ONH2‐dNTPs compared to the wild‐type enzyme.
Chengjie Zhang, Lei Du, Shengying Li
wiley +1 more source
Validation of blood vitamin A concentrations in cattle: comparison of a new cow-side test (iCheck™ FLUORO) with high-performance liquid chromatography (HPLC). [PDF]
Raila J +6 more
europepmc +1 more source
In anaerobic bacteria, tyrosine serves as an electron donor in the oxidative Stickland fermentation branch, generating p‐hydroxyphenylacetate, ATP and reduced ferredoxin for decarboxylation into p‐cresol. ABSTRACT The phenolic metabolite p‐cresol is a byproduct of tyrosine fermentation by certain strictly anaerobic bacteria, including the human gut ...
Li Jiang +15 more
wiley +1 more source

