Advanced Science, EarlyView.Receptor‐triggered supramolecular self‐assembly converts monovalent antibody‐recruiting molecules into multivalent platforms directly on cancer cell membranes. The resulting fibrillar assemblies present clustered haptens that efficiently recruit endogenous antibodies, enabling selective complement‐mediated immune killing of EGFR‐positive cancer cells ...
Yihui Wang +6 more
wiley +1 more source
Analytical Quality by Design-Based Reverse-Phase High-Performance Liquid Chromatography Method Development for Biomarker: A Comprehensive Review of Quality Assessment and Analytical Trends. [PDF]
Biomed ChromatogrPatil SB, Sutar SB, Bhimanwar R.
europepmc +1 more source
Orthogonal Light‐ and Enzyme‐Triggered and‐Gate Prodrugs for Senolytic Therapy
Advanced Science, EarlyView.An orthogonal AND‐gate prodrug platform combines 390 nm near‐UV photocleavage with SA‐β‐gal activation to control payload release in senescent cells. Its modular architecture enables 4‐MU fluorescence, doxorubicin‐mediated cytotoxicity, and ARV‐771‐driven BRD4 degradation, supporting stimulus‐controlled senolytic design in cellular and organoid models.
Mengyang Chang +12 more
wiley +1 more source
Phenolic Antioxidants in Food: A Comparative Review of Chromatographic, Spectroscopic, and Electrochemical Detection Methods. [PDF]
FoodsZhao Y, Lu Q, Tu J, Zhao Z, Zou B.
europepmc +1 more source
Assay of LDH Isoenzyme with High Performance Liquid Chromatography (HPLC).
Japanese Journal of Clinical Chemistry, 1980 MATSUMOTO, KOJIRO +2 more
openaire +1 more source
Autonomous AI‐Driven Design for Skin Product Formulations
Advanced Intelligent Discovery, EarlyView.This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang +5 more
wiley +1 more source
Comparative analysis of enzymatic assay for HbA1c measurement with high performance liquid chromatography. [PDF]
Sci RepRani GF, Bilal H, Jabeen S, Taj AS.
europepmc +1 more source
Animal Models and Experimental Medicine, EarlyView.This study demonstrates that kojic acid–loaded nanostructured lipid carriers (KA‐NLC) provide significant neuroprotection in a male rat model of middle cerebral artery occlusion (MCAO)–induced stroke. Treatment with KA‐NLCs reduced cerebral edema, improved motor and coordination balance and neurological scores, and enhanced spatial and avoidance memory.
Mobina Gheibi +11 more
wiley +1 more source
pH‐Responsive Ultrasmall Iron Oxide Nanoassemblies for Activatable T2/T1 Magnetic Resonance Imaging
Advanced NanoBiomed Research, EarlyView.This research reports a pH‐responsive ultrasmall iron oxide nanoparticle (USIONs)/polymer nanoassemblies for activatable magnetic resonance imaging. Amphiphilic diphosphonic acid block copolymers compactly encapsulate USIONs to generate T2‐weighted contrast at physiological pH, while acidic conditions trigger disassembly, activating T1‐weighted ...
Xumin Huang +11 more
wiley +1 more source
Green Solvent-Based Dispersive Liquid-Liquid Microextraction Method Coupled with High-Performance Liquid Chromatography for the Determination of Triazole Fungicides in Cereal Samples. [PDF]
FoodsLi M, Wang Y, Yin H, Jing X, Li Y.
europepmc +1 more source