Results 61 to 70 of about 404,733 (304)

Principles of High Performance Liquid Chromatography (HPLC)

open access: yes, 2021
HPLC is one of the most common separation techniques in many sciences. This paper first refers to the history of chromatography, its terms and relationships, and then to the careful selection of instrumental and laboratory parameters in order to perform an efficient separation. Parameters such as the choice of column type and the choice of moving phase,
openaire   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

In Situ Constructed Magnetic Core‐Shell Hydrogen‐Bonded Organic Framework‐on‐Metal–Organic Framework Structure: an Efficient Catalyst for Peroxymonosulfate Activation

open access: yesAdvanced Functional Materials, EarlyView.
In this work, a magnetic core‐shell catalyst (HOF‐on‐Fe3O4/ZIF‐67) is successfully synthesized, consisting of a metal–organic framework (ZIF‐67) with magnetic Fe3O4 as the core and a porous hydrogen‐bonded organic framework (HOF) as the shell. The catalyst efficiently activated peroxymonosulfate, resulting in rapid and effective removal of water ...
Yingying Du   +4 more
wiley   +1 more source

Implementation of a single quad MS detector in routine QC analysis of peptide drugs

open access: yesJournal of Pharmaceutical Analysis, 2016
A newly developed single quad mass spectrometry (MS) detector was coupled to a ultra-high performance liquid chromatography (UPLC) system and implemented in the routine quality control (QC) and impurity analysis of four therapeutic peptides, namely ...
Matthias D’Hondt   +3 more
doaj   +1 more source

Sorghum Carotenoid Variation [PDF]

open access: yes, 2019
Purpose The purpose of this research is to understand the heritability and genetic controls of sorghum grain carotenoids in order to develop a biofortification plan.
Bach, Tory   +3 more
core  

Liquid chromatographic strategies for separation of bioactive compounds in food matrices [PDF]

open access: yes, 2018
Nowadays, there is an increasing attention for nutraceuticals and, in general, bioactive compounds naturally present in food. Indeed, the possibility of preserving human health and preventing disease (e.g., cardiovascular diseases, cancer etc.) by the ...
Capriotti, Anna Laura   +5 more
core   +1 more source

Selective and Precise Editing of Digital Polymers Through Parallel or Series Toehold‐Mediated Strand Displacement

open access: yesAdvanced Functional Materials, EarlyView.
A sequence‐encoded supramolecular construct containing two accessible toeholds is developed herein for enabling multiple editing operations. By introducing specific input strands, it is possible to selectively erase or rewrite digital content through parallel or series toehold‐mediated strand displacement (PTMSD or STMSD).
Jakub Ossowski   +3 more
wiley   +1 more source

ANALYTICAL FEATURES OF SYNTHETIC MDMB(N)-073F CANNABIMIMETICS AND ITS MARKERS IN BIOLOGICAL MATERIAL

open access: yesФармация и фармакология (Пятигорск), 2019
The aim of the research is to study both analytical features of synthetic MDMB(N)-073F cannabimimetics of indazole carboxamides group by gas chromatography methods combined with tandem mass spectrometry (GC-MS) and high performance liquid chromatography ...
S. S. Kataev   +4 more
doaj   +1 more source

Analysis of ochratoxin A in pig tissues using high pressure liquid chromatography (HPLC) and liquid chromatography tandem mass spectrometry (LC/MS/MS) as confirmative methods [PDF]

open access: yesZbornik Matice Srpske za Prirodne Nauke, 2009
Two different analytical methods for the determination and confirmation of ochratoxin A (OTA) in blood serum, kidney and liver of pigs have been compared. Sample clean-up was based on liquid-liquid phase extraction.
Milićević Dragan R.   +4 more
doaj   +1 more source

A Modified Potency Test Strategy for IV Admixtures Prepared by Robotic Systems [PDF]

open access: yes, 2015
Introduction: Robotic systems are increasingly used for compounding sterile IV admixtures (1-5). In addition to routine gravimetric checks, initial and periodic drug potency analysis by high-performance liquid chromatography (HPLC) is desired to verify ...
Dave, Vivek S   +2 more
core   +1 more source

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