Results 221 to 230 of about 153,197 (305)

One‐Pot Synthesis of a Small Synthetic Ligand for Antibody Purification

open access: yesBiotechnology and Bioengineering, EarlyView.
One‐pot liquid‐phase synthesis of the synthetic ligand B1Al2A2 enables controllable ligand density and efficient capture of IgG and IgY with high recovery and purity, streamlining small‐ligand affinity purification workflows. ABSTRACT The development of synthetic affinity ligands offers a cost‐effective alternative to traditional biological ligands ...
Carolina Mota Natal   +8 more
wiley   +1 more source

Mechanistic elucidation of HFIP‐enabled C–Cl bond activation in the synthesis of tetrahydroquinoline derivatives

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Mechanistic studies reveal that hexafluoroisopropanol (HFIP) enables C–Cl activation of propargylic halides by stabilizing ion pairs and enhancing effective Brønsted acidity. This cooperative solvent effect allows access to cationic intermediates and promotes cascade formation of tetrahydroquinolines through cyclization and disproportionation ...
Seung Hoon Lee, Hyung Min Chi
wiley   +1 more source

Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation

open access: yesBMEMat, EarlyView.
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu   +12 more
wiley   +1 more source

Marine silicon for biomedical sustainability

open access: yesBMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han   +3 more
wiley   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

open access: yesBMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong   +11 more
wiley   +1 more source

Carbon‐Supported Dual‐Nickel Atom Catalysts With Stabilized Ni─N3 Active Sites for Efficient CO2 Electroreduction

open access: yesCarbon Energy, EarlyView.
Dual‐nickel atom catalysts (Ni‐DACs) are developed to stabilize unsaturated Ni─N3 atomic sites by constructing N3Ni─NiN3 dual‐atom structures from coal. Benefiting from the modulated electronic structure that optimizes intermediate adsorption, Ni‐DACs outperform Ni‐SACs in CO2 electroreduction, achieving a max FECO of 98.6% at −0.8 V vs RHE and a TOF ...
Jiabao Niu   +8 more
wiley   +1 more source

Spectroscopic Insights Into the Role of the Coverage of *CO and *H on Bifurcation of Ethylene and Ethanol Pathways in Carbon Dioxide Electroreduction

open access: yesCarbon Energy, EarlyView.
Zhao et al. control the coverage of *CO or *H intermediates by introducing foreign metal into Cu nanoparticles. The increased *CO coverage on Ag‐doped and Zn‐doped Cu promotes the generation of multi‐carbon products while the increased *H coverage of Co‐doped and Pd‐doped Cu enhances the selectivity of oxygenates. ABSTRACT As key reaction intermediates
Zi‐Hao Zhao   +3 more
wiley   +1 more source

Biomass‐Coupled HER System: A Strategy for Sustainable and Low‐Cost Hydrogen Production

open access: yesCarbon Energy, EarlyView.
Pine wood is carbonized into a hierarchically porous biochar anode that undergoes carbon oxidation reaction, replacing the oxygen evolution reaction in alkaline water electrolysis. The resulting biomass‐coupled HER system converts water into hydrogen at low cell voltages, enabling low‐cost H2 production from renewable carbon resources. ABSTRACT Biomass‐
Yuming Huang   +10 more
wiley   +1 more source

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