Results 81 to 90 of about 6,298,750 (294)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
A Neural Algorithm of Artistic Style
, 2015 In fine art, especially painting, humans have mastered the skill to create unique visual experiences through composing a complex interplay between the content and style of an image.
Bethge, Matthias +2 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Libra: An Economy driven Job Scheduling System for Clusters
, 2002 Clusters of computers have emerged as mainstream parallel and distributed platforms for high-performance, high-throughput and high-availability computing.
Ali, Nosheen +4 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Cross-Level Relationship of Implemented High Performance Work System and Employee Service Outcomes: The Mediating Role of Affective Commitment [PDF]
Pakistan Journal of Commerce and Social Sciences, 2017 This study examines cross-level relationship between implemented high performance work system (HPWS) and employee service related behaviors along with the mediating effects of employees’ affective commitment between this relationship.
Amir Riaz (Corresponding author)
doaj
Initial explorations of ARM processors for scientific computing
, 2014 Power efficiency is becoming an ever more important metric for both high performance and high throughput computing. Over the course of next decade it is expected that flops/watt will be a major driver for the evolution of computer architecture.
Abdurachmanov, David +3 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A Many-Core Overlay for High-Performance Embedded Computing on FPGAs [PDF]
, 2014 In this work, we propose a configurable many-core overlay for high-performance embedded computing. The size of internal memory, supported operations and number of ports can be configured independently for each core of the overlay.
Neto, Horácio, Véstias, Mário
core +1 more source
Efficient Detectors for MIMO-OFDM Systems under Spatial Correlation Antenna Arrays
, 2018 This work analyzes the performance of the implementable detectors for multiple-input-multiple-output (MIMO) orthogonal frequency division multiplexing (OFDM) technique under specific and realistic operation system condi- tions, including antenna ...
Abrao, Taufik +3 more
core +1 more source