Results 51 to 60 of about 167,216,277 (246)
Energies, 2018 District heating plays a key role in achieving high primary energy savings and the reduction of the overall environmental impact of the energy sector.
Borna Doračić +3 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Design and Testing of Heat Pipe Based Cooling Solution for Efficient Thermal Management of FPGA on Space Application [PDF]
MATEC Web of ConferencesThe rapid advancement of high-density electronics, such as Field-Programmable Gate Arrays (FPGA), requires efficient thermal management to ensure optimal performance, especially in space applications, where conventional cooling methods like convection ...
Joteppa Santosh +2 more
doaj +1 more source
The influence of return bends on the downstream pressure drop and condensation heat transfer in tubes [PDF]
, 1971 The influence of return bends on the downstream pressure drop and heat transfer coefficient of condensing refrigerant R-12 was studied experimentally. Flow patterns in glass return bends of 1/2 to 1 in. radius and 0.315 in. I. D.
Traviss, Donald P., Rohsenow, Warren M.
core
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Experimental and Numerical Study on a Dry-expansion Shell-and-Tube Evaporator Used in Wastewater Source Heat Pump (WWSHP) [PDF]
, 2012 Aiming at the issue of bio-fouling build-up on heat exchanger\u27s surface in wastewater source heat pump (WWSHP) systems, a novel dry-expansion shell-and-tube wastewater evaporator (DESTE) with defouling function was developed.
Wang, Xinlei +3 more
core +1 more source
EnergiesThis paper presents the design and experimental investigation of an indirect regenerative evaporative cooling (IREC) system based on the M-cycle concept for electronic systems operating in high ambient temperature. The proposed heat exchanger consists of
Maria Strąkowska +6 more
doaj +1 more source
Shift a laser beam back and forth to exchange heat and work in thermodynamics
Scientific Reports, 2021 Although the equivalence of heat and work has been unveiled since Joule’s ingenious experiment in 1845, they rarely originate from the same source in experiments. In this study, we theoretically and experimentally demonstrated how to use a high-precision
John A. C. Albay +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source