Results 71 to 80 of about 167,216,277 (246)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

The potential of high heat generating granites as EGS source to generate power and reduce CO2 emissions, western Arabian shield, Saudi Arabia

, 2015
Saudi Arabia's dependence on oil and gas to generate electricity and to desalinate sea water is widely perceived to be economically and politically unsustainable.
Varun, C., Singh, H. K., Chandrasekharam, D., Al Arifi, N., Al Bassam, A., Lashin, A., El Alfy, M., Ranjith, P. G.   +7 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

A Key Review of Non-Industrial Greywater Heat Harnessing

Energies, 2018
The ever-growing concerns about making buildings more energy efficient and increasing the share of renewable energy used in them, has led to the development of ultra-low carbon buildings or passive houses.
Abdur Rehman Mazhar, Shuli Liu, Ashish Shukla   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Cooling of high-power-density computer components [PDF]

, 1968
This report summarizes work carried out during the first two years of a research program sponsored by IBM Corporation. This study has elucidated a number of the heat-transfer characteristics of several fluorochemicals which have potential application as ...
Bakhru, N., Bergles A. E., Shires, J. W.   +2 more
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Harnessing Geothermal Energy Potential from High-Level Nuclear Waste Repositories

Energies
The disposal of high-level nuclear waste (HLW) has been one of the most challenging issues for nuclear energy utilization. In this study, we have explored the potential of extracting decay heat from HLW, taking advantage of recent advances in the ...
Dauren Sarsenbayev, Liange Zheng, Dinara Ermakova, Rashid Sharipov, Haruko M. Wainwright   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Experimental Results of a Newly Developed Very High Temperature Industrial Heat Pump (140°C) Equipped With Scroll Compressors and Working With a New Blend Refrigerant [PDF]

, 2012
During last decades more and more attention has been paid on CO2 emissions. One of the solutions for decreasing CO2 emissions concerns the substitution of fossil fuels industrial boilers by the use of very high temperature electrical heat pumps. Moreover,
Bourig, Ali, Bobelin, Damien
core   +1 more source