Results 151 to 160 of about 26,525,554 (339)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
High power switching transistor Final report [PDF]
Design theory and fabrication procedure for n-p-n 100 ampere silicon switching ...
Beaudouin, J., Finch, R.
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Application of 12 MW High-power Soft-starter Equipment in Plateau Refinery
According to the starting demand of high-voltage motor with 6 kV/12 MW which applied in a refinery for the energy recovery unit in high-altitude region, a soft-starter is designed for starting two motors, and the system parameters are calculated by the ...
林丽, 张铁军, 张少云, 陈刚
doaj
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
The activities of the High Power Arcjet Project (HIPARC) from August 1990 to January 1991 are discussed. In this period the HIPARC thruster was ignited for the first time. Power levels up to 140 kW with a mass flow rate of 300 mg/s hydrogen were reached.
Auweter-Kurtz, M. +3 more
core +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
High power diode lasers at 1470 nm with continuous power exceeding 10 W
High power InP-based diode lasers operating at 1470 nm have attracted considerable interest in various applications. In this paper, we report high-power lasers with varying stripe widths, which employ an extremely asymmetric epitaxial design for high ...
Rong Zhao +9 more
doaj +1 more source

