Results 131 to 140 of about 20,813,737 (316)

Cell-level power supply for high-voltage modular multilevel converters

open access: yes, 2017
Focus is on the design and development of an auxiliary power supply converter for HVDC and FACTS applications, utilising integrated gate-commutated thyristors.
Blinov, Andrei,   +10 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

2016 CPES Annual Report

open access: yes, 2016
In its effort to develop power processing systems to take electricity to the next step, CPES has cultivated research expertise encompassing five technology areas: (1) power conversion technologies and architectures; (2) power electronics components; (3 ...
Center for Power Electronics Systems   +1 more
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

2017 CPES Annual Report

open access: yes, 2017
In its effort to develop power processing systems to take electricity to the next step, CPES has cultivated research expertise encompassing five technology areas: (1) power conversion technologies and architectures; (2) power electronics components; (3 ...
Center for Power Electronics Systems   +1 more
core  

High frequency high power converters for industrial applications [PDF]

open access: yes, 2013
The main contribution of this project was to investigate power electronics technology in designing and developing high frequency high power converters for industrial applications. Therefore, the research was conducted at two levels; first at system level
Davari, Pooya
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Application of 12 MW High-power Soft-starter Equipment in Plateau Refinery

open access: yesKongzhi Yu Xinxi Jishu, 2010
According to the starting demand of high-voltage motor with 6 kV/12 MW which applied in a refinery for the energy recovery unit in high-altitude region, a soft-starter is designed for starting two motors, and the system parameters are calculated by the ...
林丽, 张铁军, 张少云, 陈刚
doaj  

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