This work presents an injectable polymer‐nanoparticle hydrogel depot platform for delivering multivalent influenza vaccines which induces stronger and more durable immune responses. The technology provides broader protection, including against heterologous and potential pandemic strains (H5N1, H7N9, H9N2), and enhances the effectiveness of commercial ...
Olivia M. Saouaf+7 more
wiley +1 more source
Comparison of the BioRad Variant and Primus Ultra2 high-pressure liquid chromatography (HPLC) instruments for the detection of variant hemoglobins [PDF]
Robert C. Gosselin+2 more
openalex +1 more source
The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ
The placenta expresses much higher levels of PPARγ than fetal adipose tissue. Trophoblastic exosomes transport PPARγ into fetal preadipocytes via fetoplacental circulation and thus regulate adipogenic genes distinct from endogenous PPARγ. Compromised placental PPARγ leads to fetal adipogenesis deficiency and intrauterine growth restriction, reversible ...
Xiaofang Luo+17 more
wiley +1 more source
T‐Cell‐Dependent Bispecific IgGs Protect Aged Mice From Lethal SARS‐CoV‐2 Infection
This study describes the development of spike‐targeting T‐cell‐dependent bispecific full‐length human immunoglobulin Gs with enhanced efficacy in the treatment of COVID‐19. The significance of T‐cell‐based immunity during infection is highlighted. These results have significant implications for better clinical effectiveness of therapies for COVID‐19 ...
Wenyan Fu+8 more
wiley +1 more source
Screening and Identification of the Metabolites in Rat Plasma and Urine after Oral Administration of Areca catechu L. Nut Extract by Ultra-High-Pressure Liquid Chromatography Coupled with Linear Ion Trap-Orbitrap Tandem Mass Spectrometry. [PDF]
Li L+10 more
europepmc +1 more source
Determination of Hexestrol in Ointment by High-pressure Liquid Chromatography
JUNKO KATSUDA+5 more
openalex +2 more sources
Approximate and Exact Equations for Peak Capacity in Isocratic High-Pressure Liquid Chromatography [PDF]
Lawrence W. Potts, Peter W. Carr
openalex +1 more source
Developing Quorum Sensing‐Based Collaborative Dynamic Control System in Halomonas TD01
A standardized and streamlined inducer‐free quorum sensing (QS)‐based collaborative dynamic control pattern is developed for sufficient gene expression control in Halomonas TD by mixing two engineered cells, cells A and B. Proof‐of‐concept studies are designed to test the dynamic control performance in mixed cultures in fed‐batch conditions.
Yi‐Na Lin+12 more
wiley +1 more source
Chemical Profiling of Constituents of Smilacis glabrae Using Ultra-high Pressure Liquid Chromatography Coupled with LTQ Orbitrap Mass Spectrometry [PDF]
Xiong Li+6 more
openalex +1 more source
Cyclosporin G analysis and monitoring by high pressure liquid chromatography [PDF]
Burckart, GJ+5 more
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