Results 321 to 330 of about 435,222 (363)
Some of the next articles are maybe not open access.
Trends in High Pressure Liquid Chromatography
Berichte der Bunsengesellschaft für physikalische Chemie, 1973AbstractThe recent developments of high pressure liquid chromatography are reviewed with the emphasis on the main problems with which the users of this technic are faced: the design of more sensitive, specific detectors, the design of systems to prepare reproducible solvent gradients and to detect small concentrations of compounds in a variable ...
openaire +2 more sources
Assay of Cefotaxime by High-Pressure-Liquid Chromatography
Chemotherapy, 1981A high-pressure-liquid chromatographic (HPLC) procedure for quantitative assay of cefotaxime (CT) and its major metabolite in serum of normal individuals, desacetyl cefotaxime (DACT), is described. It employs Lichrosorb RP-8, elution with phosphoric-acid-methanol and UV absorption at 310 nm.
Tom Bergan, Rita Solberg
openaire +3 more sources
Determination of Thiopental by High Pressure Liquid Chromatography
Acta Pharmacologica et Toxicologica, 1979AbstractA specific and rapid reverse phase HPLC‐method for the determination of thiopental in serum and in protein free solutions is described. No extraction is used. The detection limit is about 0.090 μg/ml for serum and about 0.030 μg/ml for buffer solutions. The retention time is 3.80 min.
J. Heslop Christensen +1 more
openaire +2 more sources
A fluorescence detector for high-pressure liquid chromatography
Journal of Chromatography A, 1977We describe a fluorescence spectrophotometer adapted with a micro quartz flow cell to record the output of modern liquid chromatographs. The optical system is double beam in that the light source variations are cancelled out by a second photomultiplier, thus enhancing the sensitivity of the technique. The emission spectra may be scanned by stopping the
W. Slavin +2 more
openaire +3 more sources
Journal of Chromatography A, 2014
This is the first investigation in a series that aims to enhance the scientific knowledge needed for reliable analytical method transfer between HPLC and UHPLC using the quality by design (QbD) framework. Here, we investigated the differences and similarities from a thermodynamic point of view between RP-LC separations conducted with 3.5μm (HPLC) and 1.
Krzysztof Kaczmarski +4 more
openaire +3 more sources
This is the first investigation in a series that aims to enhance the scientific knowledge needed for reliable analytical method transfer between HPLC and UHPLC using the quality by design (QbD) framework. Here, we investigated the differences and similarities from a thermodynamic point of view between RP-LC separations conducted with 3.5μm (HPLC) and 1.
Krzysztof Kaczmarski +4 more
openaire +3 more sources
High-pressure liquid chromatography of peptides and proteins
Journal of Chromatography A, 1978Abstract This report describes the use of hydrophobic ion-pairing reagents in the rapid analysis of peptides by reversed-phase high-pressure liquid chromatography. It was found that combination of a hydrophobic anion such as hexanesulphonate with the cationic groups (R P + of a peptide resulted in a decreased polarity of the sample. This change
David R. K. Harding +4 more
openaire +3 more sources
High Pressure Liquid Chromatography of Eicosanoids
1985Arachidonic acid (20:4) and other polyunsaturated fatty acids can be oxygenated in many tissues by cyclooxygenase or a variety of lipoxygenases. The intermediates formed in these reactions are then converted enzymatically to a variety of other products.
openaire +2 more sources
Forensic aspects of high-pressure liquid chromatography
Journal of Chromatography A, 1976This paper reviews the applications of high-pressure liquid chromatography (HPLC) to forensic problems, and discusses some of the developments that have taken place in the use of the technique in the Metropolitan Police Laboratory. Preparation of octadecyltrichlorosilane-modified silica is described and some of the chromatographic characteristics of ...
openaire +3 more sources
Analysis of vitamin A in eggs by high pressure liquid chromatography
Food / Nahrung, 1991AbstractA high speed liquid chromatographic method was described for the rapid determination of vitamin A in eggs. After saponification and extraction, the sample was separated on a reversed‐phase column (C18) with acetonitrile ‐ methylene‐chloride ‐ methanol as the mobile phase. Quantitative determination was accomplished by monitoring the ultraviolet
Hisil Y., Ötles S.
openaire +3 more sources
ChemInform Abstract: LIQUID‐LIQUID PARTITION COEFFICIENTS BY HIGH‐PRESSURE LIQUID CHROMATOGRAPHY
Chemischer Informationsdienst, 1975Lipid-water partition values can be rapidly and reliably measured by high-pressure liquid chromatography (HPLC) on bonded octadecylsialne supports. This method has been developed and applied to a family of hypotensive triaminopyrimidine 3-oxides. The measured column retention values for this class of compounds correlate well with the values calculated ...
openaire +4 more sources