Results 341 to 350 of about 719,896 (409)

High-pressure liquid chromatography in polynucleotide synthesis.

Biochemistry, 1978
Reverse phase high-pressure liquid chromatography (HPLC) using columns containing microparticulate materials with bonded octadecyl groups has been developed as a rapid and efficient method for the separation of nucleosides, nucleotides, and, in ...
H. Fritz, R. Belagaje, E. Brown, R. Fritz, R. Jones, R. G. Lees, H. Khorana   +6 more
semanticscholar   +1 more source

Anthracycline Assay by High-pressure Liquid Chromatography

Journal of Pharmaceutical Sciences, 1981
A general method of analysis of anthracycline concentrations was developed. Drug is extracted from plasma with organic solvent and separated from metabolites by high-pressure liquid chromatography on an aminocyanosilica column. Detection and quantitation are by the endogenous fluorescence of compounds having an intact tetracyclic ring structure. Limits
Steven D. Averbuch, Steven D. Reichx, Steven D. Reichx, Susan E. Fandrich, Theodore T. Finkelstein   +4 more
openaire   +3 more sources

High pressure liquid chromatography of neutral glycosphingolipids

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1972
Abstract A system for the separation of neutral glycosphingolipids by high pressure liquid chromatography of their benzoylated derivatives has been devised. Serum mono-, di-, tri-and tetraglycosylceramides are completely resolved within 25 min. A full scale recorder response can be obtained with approximately 1.0 nmole of glycolipid.
James E. Evans, Robert H. McCluer
openaire   +3 more sources

Liquid-lipquid partition coefficients by high-pressure liquid chromatography.

Journal of Medicinal Chemistry, 1975
Lipid-water partition values can be rapidly and reliably measured by high-pressure liquid chromatography (HPLC) on bonded octadecylsialne supports. This method has been developed and applied to a family of hypotensive triaminopyrimidine 3-oxides.
J. Mccall
semanticscholar   +1 more source

Yeast mutants blocked in removing the methyl group of lanosterol at C-14. Separation of sterols by high-pressure liquid chromatography.

Biochemistry, 1977
Sterols of a nystatin resistant mutant of the wild type parent of Saccharomyces cerevisiae were separated by a newly developed procedure involving high-pressure liquid chromatography and were identified.
P. Trocha, S. Jasne, D. B. Sprinson
semanticscholar   +1 more source

Analysis of Trisulfapyrimidines by High-Pressure Liquid Chromatography

Journal of Pharmaceutical Sciences, 1973
Abstract: The application of high-pressure liquid chromatography to the separation and analysis of trisulfapyrimidines in pharmaceutical dosage forms is demonstrated. The preparation of samples of both tablet and suspension dosage forms is simple and rapid.
Henry H. Pu, Raymond B. Poet
openaire   +3 more sources

Quantitation of amphotericin B with use of high-pressure liquid chromatography.

Journal of Infectious Diseases, 1977
A chemical method for determination of concentrations of amphotericin B in serum and cerebrospinal fluid (CSF) is described. After extraction with methanol, the antibiotic was separated by reverse-phase, high-pressure liquid chromatography and ...
I. Nilsson-ehle, T. Yoshikawa, J. Edwards, M. Schotz, L. B. Guze   +4 more
semanticscholar   +1 more source

Mexiletine in Plasma by High Pressure Liquid Chromatography

Therapeutic Drug Monitoring, 1981
We report here a novel high pressure liquid chromatographic (HPLC) technique for use in therapeutic monitoring of the primary amine antiarrhythmic drug mexiletine in plasma samples. Mexiletine and its structural analogue, the internal standard Ko 768, are extracted with heptane after alkalinization of the sample. The extracts are evaporated to dryness,
Christmore D, Kelly R, Smith R, Doshier L, Jacobs Sl   +4 more
openaire   +3 more sources

Reversed-phase, high-pressure liquid chromatography of peptides and proteins with ion-pairing reagents.

Science, 1978
Reversed-phase, high-pressure liquid chromatography has been successfully applied to the analysis of peptides and proteins by the addition of hydrophilic (for example, phosphoric acid) or hydrophobic (for example, hexanesulfonic acid) ion-pairing ...
W. Hancock, C. A. Bishop, RL Prestidge, Harding, M. Hearn   +4 more
semanticscholar   +1 more source

Assay of Cefotaxime by High-Pressure-Liquid Chromatography

Chemotherapy, 1981
A high-pressure-liquid chromatographic (HPLC) procedure for quantitative assay of cefotaxime (CT) and its major metabolite in serum of normal individuals, desacetyl cefotaxime (DACT), is described. It employs Lichrosorb RP-8, elution with phosphoric-acid-methanol and UV absorption at 310 nm.
Tom Bergan, Rita Solberg
openaire   +3 more sources