Results 91 to 100 of about 2,698,288 (314)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The estimation value of China’s agricultural high-quality development.
The estimation value of China’s agricultural high-quality development.
Chenjing Zhou (289360) +5 more
core +1 more source
Measurement of the high-quality development level of China's marine economy
, 2021 Purpose - The purpose of this paper is to measure the high-quality development level of China's marine economy and analyze corresponding spatial and temporal distribution characteristic.
Liu, Huichao +3 more
core +1 more source
Scientific ReportsCounties represent a crucial spatial unit for achieving integrated urban-rural development and coordinated regional development. Promoting new urbanization(NU) at the county level in special-type regions such as revolutionary old base areas is an ...
Xiao Fu, Yingmin Huang
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Fast Development of High-Quality Vaccines in a Pandemic [PDF]
Chest, 2021 Pischel, Lauren +2 more
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Evaluation index system for high-quality development of service industry.
Evaluation index system for high-quality development of service industry.
Chenfei Duan (18086566) +5 more
core +1 more source
, 2021 Different from the developmental mode of western developed countries, China’s economy has changed from a stage of high-speed growth to a stage of high-quality development, where the people’s growing needs for better lives can be met, embodying this new ...
Xiangyu Hua, Xiangrong Jin, Haiping Lv
core +1 more source
Data in Brief, 2020 This article presents data on the effects of spacing and fruit truss limitation on tomato plant growth, yield and fruit quality. Plants with two, three, and four fruit trusses (T1-T3) were grown in four different spaces (S1-S4) to create 12 treatments ...
Long Thien Tran +7 more
doaj +1 more source