Results 91 to 100 of about 2,716,701 (268)

Agriculture High Quality Development and Nutrient

Food Science & Nutrition Research
Since 2017, China development had entered a new stage of high-quality development, so, Agriculture development had entered the new stage of high-quality development. Agriculture high quality development is to take some measures and methods to make the land produce the maximum output and services to meet people's yearning for a better life and ...
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Effectiveness of long-term cluster training and traditional resistance training in enhancing maximum strength in young adults: a systematic review and meta-analysis

Frontiers in Physiology
BackgroundIt is still unclear whether traditional resistance training (TRT) provides the best or optimal stimulation for increasing maximum strength compared to cluster training (CT).ObjectiveThis study assessed the long-term impact of cluster training ...
Jiayue Cui, Jiayue Cui, Yin Yu, Yin Yu, Yijun Xu, Hongyu Wu   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Systematic synthesis of CRISPR/Cas applications for enhancing salt tolerance in crops: a decade of progress and challenges

BMC Plant Biology
Soil salinity is a major constraint on global crop productivity, driving the need for salt-tolerant varieties. While CRISPR-Cas genome editing offers targeted solutions for trait improvement, significant biological and technical bottlenecks limit its ...
Xindi Sun, Fusheng Wu, Zhuanzhuan Ma, Guohao Liang, Shumei Chen, Xutong Hu, Shugao Fan, Ying Zhao   +7 more
doaj   +1 more source

Examining the dynamic and nonlinear impacts of public health events on the resilience of food supply chain: evidence from China

Frontiers in Sustainable Food Systems
IntroductionThe fragility of agriculture makes the food supply chain vulnerable to external risks such as epidemic, conflict, disaster, climate change, economic and energy crisis.
Jingdong Li, Jingdong Li, Zhi Li, Zilong Shi, Hongjun Geng   +4 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Silicon and Zinc Fertilizer Application Improves Grain Quality and Aroma in the japonica Rice Variety Nanjing 46

Foods
This study examined how silicon and zinc fertilizers affect the quality and aroma of Nanjing 46. We applied nine different fertilizer treatments, one involving soil topdressing at the top fourth leaf-age stage and one involving foliar spraying during the
Xiaodong Wei, Yadong Zhang, Xuemei Song, Ling Zhao, Qingyong Zhao, Tao Chen, Kai Lu, Zhen Zhu, Shengdong Huang, Cailin Wang   +9 more
doaj   +1 more source