Results 131 to 140 of about 2,698,288 (314)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Sustainable FuturesSustainable development is the key to achieving high-quality growth in the manufacturing industry. The article analyzes the impact of energy inputs and carbon emission constraints on the ESG performance of Chinese manufacturing firms using listed company
Sen Wang, Jinye Li
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Re-examining virtual water transfer in the Yellow River Basin, China
Journal of Hydrology: Regional StudiesStudy region: The Yellow River Basin (a water-deficient region) in China. Study focus: The redistribution of virtual water through trade holds potential to enhance water security in the Yellow River Basin.
Huimin Yang +4 more
doaj +1 more source
Development of High Quality No Fine Concrete
JOURNAL OF ADVANCES IN NATURAL SCIENCES, 2016 Natural sand is being extorted at an increasing rate. Construction industry is looking for an alternative material for sand and research is going on to find new innovative concrete. No fines concrete has been generally used for paving applications, other non-structural application, such as reinforced panels, acoustic, thermal and permeability ...
openaire +2 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Frontiers in Marine ScienceUsing social network analysis, spatial econometric method and structural equation model, based on the patent citation data of China’s marine industry from 2008 to 2019, this paper analyzes the temporal-spatial characteristics and influencing factors of ...
Kai Liu +7 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source