Results 191 to 200 of about 2,698,288 (314)

Correction: Recent advances in training intensity distribution theory for cyclic endurance sports: theoretical foundations, model comparisons, and periodization characteristics

Frontiers in Physiology
Qihao Sun, Qihao Sun, Yin Yu, Yin Yu, Jiayue Cui, Jiayue Cui, Simin Lin, Simin Lin, Xiaohan Wang, Xiaohan Wang, Tian Zhou, Tian Zhou   +11 more
doaj   +1 more source

Research on the coupling coordination of high-quality development and carbon emission in China's construction industry. [PDF]

Sci Rep
She W, Cao L, Zhu Y.
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Spatiotemporal analysis and driving force of high quality development of small towns in Guangxi, China. [PDF]

Sci Rep
Hu C, Liu B, Yan Z, Ma C.
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Energy Conservation and Emission Reduction in Central Sterile Supply Department Under High-Quality Development of Public Hospitals: A Narrative Review. [PDF]

J Healthc Leadersh
Zhang HQ, Cheng P, Ji FH, Sudhan N, Peng K.   +4 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Study on the Influence of New Quality Productivity on the High-Quality Development of Marine Economy

The construction of marine power is inevitable to realize the high-quality development of the marine economy, and the development of new quality productive forces provides help for the high-quality development of the marine economy in China. Based on the
XU Handuo, YANG Shaoyang
core  

Research on the path of high-quality development of the smart health and aging care industry driven by digital economy- dynamic QCA analysis based on TOE framework. [PDF]

Front Public Health
Tan X, Shu X.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source