Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Impact mechanism and spatial spillover effect of the digital economy on the high-quality development of undertakings for the aged in China. [PDF]
Peng R, Huang M, Deng X, Wang Y.
europepmc +1 more source
High quality agrarian food products, tourism and local development. The case of Priorat
Xosé Antón Armesto, Belén Rizo Gómez
openalex +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Effects of intelligent manufacturing on the high-quality development of manufacturing industry: The mediating role of green technology innovation. [PDF]
Xu Z, Pan R.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Research on the pathways to high-quality development of tourism SMEs: A perspective of value assigned by quality, standards and brand. [PDF]
Shi J, Xiao Y.
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Identification method and application of order parameters for organizational systems considering time-series values: A case study on high-quality development in China's regional manufacturing industry. [PDF]
Wen X, Zhou Y.
europepmc +1 more source

