Results 41 to 50 of about 417,111 (255)

Ship Radial Size Estimation in High-Resolution Maritime Surveillance Radars via Sparse Recovery Using Linear Programming

open access: yesIEEE Access, 2019
For high-resolution maritime surveillance radars operating at scan mode and transmitting long duration pulses, radial size estimation of ships is severely interfered by range sidelobe effect of pulse compression. Due to range sidelobe effect, strong ship
Peng-Lang Shui, Kun Zhang
doaj   +1 more source

Design and Processing Method for Doppler-Tolerant Stepped-Frequency Waveform Using Staggered PRF

open access: yesSensors, 2021
Stepped-frequency waveform may be used to synthesize a wideband signal with several narrow-band pulses and achieve a high-resolution range profile without increasing the instantaneous bandwidth.
Yan Zhang   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Radar High-resolution Range Profile Target Recognition Based on Attention Mechanism and Bidirectional Gated Recurrent

open access: yesLeida xuebao, 2019
To address the problem of radar High-Resolution Range Profile (HRRP) target recognition, traditional methods only consider the envelope information of the sample and ignore the temporal correlation between the range cells.
LIU Jiaqi, CHEN Bo, JIE Xi
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

High-Resolution Range Profile Classifiers Require Aspect-Angle Awareness

open access: yesCoRR
We revisit High-Resolution Range Profile (HRRP) classification with aspect-angle conditioning. While prior work often assumes that aspect-angle information is incomplete during training or unavailable at inference, we study a setting where angles are available for all training samples and explicitly provided to the classifier.
Edwyn Brient   +2 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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