Results 101 to 110 of about 16,837,471 (302)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Intramolecular H-Bond Dynamics of Catechol Investigated by THz High-Resolution Spectroscopy of Its Low-Frequency Modes. [PDF]

Molecules, 2021
Bruckhuisen J, Dhont G, Roucou A, Jabri A, Bayoudh H, Tran TT, Goubet M, Martin-Drumel MA, Cuisset A.   +8 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Solid-state NMR spectroscopy on complex biomolecules [PDF]

, 2010
Biomolecular applications of NMR spectroscopy are often merely associated with soluble molecules or magnetic resonance imaging. However, since the late 1970s, solid-state NMR (ssNMR) spectroscopy has demonstrated its ability to provide atomic-level ...
NMR Spectroscopy, Baldus, M., Cukkemane, A.A., Abhishek Cukkemane, Renault, M.A.M., Sub NMR Spectroscopy, Marie Renault, Marc Baldus   +7 more
core   +1 more source

Advanced muon-spin spectroscopy with high lateral resolution using Si-pixel detectors

Physical Review Research
Muon-spin spectroscopy at continuous sources has stagnated at a stopped muon rate of ∼40kHz for the last few decades. The major limiting factor is the requirement of a single muon in the sample during the typical 10µs data gate window.
Lukas Mandok, Pascal Isenring, Heiko Augustin, Niklaus Berger, Marius Köppel, Jonas A. Krieger, Hubertus Luetkens, Thomas Prokscha, Thomas Rudzki, André Schöning, Zaher Salman   +10 more
doaj   +1 more source

Terahertz high-resolution spectroscopy of thermal decomposition gas products of diabetic and non-diabetic blood plasma and kidney tissue pellets. [PDF]

J Biomed Opt, 2021
Lykina AA, Anfertev VA, Domracheva EG, Chernyaeva MB, Kononova YA, Toropova YG, Korolev DV, Smolyanskaya OA, Vaks VL.   +8 more
europepmc   +1 more source

High Resolution Overtone Spectroscopy of HNC+ and HCN+

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
Accepted in Spectrochimica Acta Part A: Molecular and Biomolecular ...
Miguel Jiménez-Redondo, Chiara Schleif, Julianna Palotás, János Sarka, Hayley Bunn, Petr Dohnal, Paola Caselli, Pavol Jusko   +7 more
openaire   +4 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

High-Resolution Spectroscopy of High Rydberg States: Chemical and Technological Applications

CHIMIA, 2000
High Rydberg states of atoms and molecules possess unusual properties that can be exploited in chemistry and technology. The extreme sensitivity of these states to external influences makes them ideal probes of their environment and they can be ...
Frédéric Merkt
doaj   +2 more sources

High-Resolution FTIR Spectroscopy of CH₃F: Global Effective Hamiltonian Analysis of the Ground State and the 2ν₃, ν₃ + ν₆, and 2ν₆ Bands

Molecules
High-resolution Fourier transform infrared (FTIR) spectra of methyl fluoride (CH3F) were recorded in the mid- and far-infrared regions using the Bruker IFS 125HR spectrometers at GSMA (Reims, France) and at the SOLEIL synchrotron facility (Saint-Aubin ...
Hazem Ziadi, Michaël Rey, Alexandre Voute, Jeanne Tison, Bruno Grouiez, Laurent Manceron, Vincent Boudon, Hassen Aroui, Maud Rotger   +8 more
doaj   +1 more source