Results 81 to 90 of about 1,540,429 (310)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Assessing verticalization effects on urban safety perception
, 2017 We describe an experiment with the modeling of urban verticalization effects on perceived safety scores as obtained with computer vision on Google Streetview data for New York City. Preliminary results suggests that for smaller buildings (between one and
Lourenço, Ricardo Barros
core +1 more source
Patterns of Urban Housing Shape Dengue Distribution in Singapore at Neighborhood and Country Scales [PDF]
, 2018 Dengue is the most important human arboviral disease in Singapore. We classified residential areas into low-rise and high-rise housing and investigated the influence of urban drainage on the distribution of dengue incidence and outdoor breeding at ...
Chong, Chee Seng +4 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Risky facilities: analysis of crime concentration in high-rise buildings [PDF]
This paper investigates the security of high rise high density accommodation at the Gold Coast – a premier Australian holiday destination. Surfers Paradise has one of the highest population densities in Australia at 3,279 persons per square kilometre and
Benjamin Hutchins +4 more
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Impact of solar shading geometry on building energy use in hot humid climates with special reference to Malaysia [PDF]
, 2005 External solar shading devices can substantially reduce the cooling load of buildings and large energy savings can be achieved. Hence, intercepting the radiant heat wave before penetrating to the internal environment through envelope openings is the main
Ahmad, M. Hamdan +2 more
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A high-rise on Main Street: Hotelling with mobile consumers [PDF]
This note considers Hotelling’s (1929) model of locational choices by two firms and subsequent price competition in a setting where atomistic consumers locate first.
Martin Richardson
core