Results 51 to 60 of about 221,836 (297)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Buiding (High-Rise Building 1)

Wind Engineers, JAWE, 2001
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Cheng, C.-M., Lu, P.-C., Tsai, M.-S., Liang, Shuguo, Liu, Shengchun, Zhang, Liangliang, Gu, Ming, Young-Moon, Kim, Ki-Pou, You, Kawaguchi, Akihisa, Kanda, Makoto, Maruta, Eizo, Koizume, Tatuya, Tamura, Y., Matsui, M., Pagnini, Luisa-Carlotta, Ishibashi, R., Yoshida, A., Denoon, Roy O., Kwok, Kenny C. S., Roberts, Richard D.   +20 more
openaire   +3 more sources

Forced vibrations of high-rise buildings

IOP Conference Series: Materials Science and Engineering, 2020
Abstract Studies were conducted to analyze the behavior of a high-rise structure on various kinematic effects, taking into account the real geometry, dissipative and nonlinear properties of the structure material. A generalized approach was developed for the dynamic calculation of high-rise structures, and the frequency response ...
Sherzod Khudainazarov, Tulkin Mavlanov, Jakhongir Qosimov, Oliya Nurova   +3 more
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The impact of high-rise construction of urban buildings on the management of infrastructure, wastewater and urban waste with a construction management approach: Case example of Yasouj city [PDF]

مهندسی و مدیریت ساخت, 2023
The aim of the current research is the impact of high-rise urban buildings on the management of infrastructure, wastewater and urban waste with a construction management approach (case example of Yasouj city).
ali momeni manesh
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Fire safety engineering applied to high-rise building facades

MATEC Web of Conferences, 2016
Fire safety of high-rise building facades is a complex problem, therefore the use of prescriptive fire codes could not be sufficient to ensure a proper building fire safety level.
Sassi Samuele, Setti Paolo, Amaro Giuseppe, Mazziotti Lamberto, Paduano Giuseppe, Cancelliere Piergiacomo, Madeddu Mauro   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source