Results 71 to 80 of about 226,352 (268)
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
THE STUDY OF THE HIGH-RISE BUILDINGS
International Journal on Livable Space, 2019 <div class="page" title="Page 1"><div class="layoutArea"><div class="column"><p><span>One of the indicators that reflects the city's development is the rapid growth of high-rise buildings. The high price and limited available land coupled with the growth and increasingly diverse of human needs become the trigger.
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Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Dearq, 2012 This article analyses the typological transformations that took place in high-rise accommodation from the 1920’s onwards in Rosario (Argentina). The question that is posed in this paper concerns the role that the architects undertook in the previously ...
Jimena Paula Cutruneo
doaj
Cost overruns analysis in high rise building and apartment projects
Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kinh tế và Quản trị kinh doanh, 2020 Cost overruns is the lasting problem in construction industry, appears in all over the world. This research was conducted to assess the influence of each factor to the cost overruns in construction projects. The percentage of cost overruns caused by each
Nguyễn Lê Kế Nghiệp +2 more
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FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
MENGESTIMASI KOEFISIEN BUKAAN Cd PADA JENDELA BANGUNAN TINGGI DENGAN BANTUAN SIMULASI C F D
Dimensi: Journal of Architecture and Built Environment, 2001 Numerical simulation with CFD (Computational Fluid Dynamic) is actually common method for the researches on building aerodynamics. This study is focused on the observation of air movement behavior through large openings of typical high rise buildings in ...
Suryono Suryono, Sangkertadi Sangkertadi
doaj
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Journal of Disaster Research, 2007 High-rise buildings play important roles in densely populated urban areas. Those over 100 m high serve as offices, hotels, and residences. Unfortunately, fires will happen in high-rises, and, because of their size, it is difficult to determine that a fire has occurred except on the floor where it has started and is even more difficult to evacuate ...
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Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source