Results 51 to 60 of about 2,101,216 (311)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

High-Rise Building Fires

open access: yesJournal of Disaster Research, 2007
High-rise buildings play important roles in densely populated urban areas. Those over 100 m high serve as offices, hotels, and residences. Unfortunately, fires will happen in high-rises, and, because of their size, it is difficult to determine that a fire has occurred except on the floor where it has started and is even more difficult to evacuate ...
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Providing Wireless Coverage to High-rise Buildings Using UAVs

open access: yes, 2017
Unmanned aerial vehicles (UAVs) can be used as aerial wireless base stations when cellular networks go down. Prior studies on UAV-based wireless coverage typically consider an Air-to-Ground path loss model, which assumes that the users are outdoor and ...
Ji, Bo   +2 more
core   +1 more source

Energy simulations of a transparent-insulated office facade retrofit in London, UK [PDF]

open access: yes, 2012
Purpose – Transparent insulation materials (TIMs) have been developed for application to building facades to reduce heating energy demands of a building.
Eames, Philip   +2 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

RETRACTED ARTICLE: Modeling research on the effect of nano-scale admixtures on the strength of high-rise building concrete

open access: yesJournal of Experimental Nanoscience, 2023
MWCNTs and ultra-fine steel microwires double-doped RPC are researched to determine the modification law of flexural strength and post-folding compressive strength in order to investigate the impact of nanoscale admixtures on the strength of high-rise ...
Silu Yan, Hao Zhang
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Analisa Perbandingan Penggunaan Bekisting Semi Konvensional Dengan Bekisting Sistem Table Form Pada Konstruksi Gedung Bertingkat [PDF]

open access: yes, 2012
Pekerjaan bekisting memberikan kontribusi yang cukup besar dalam hal proporsi biaya pekerjaan beton. Produktifitas dan siklus dari pekerjaan bekisting juga mempengaruhi waktu pekerjaan beton. Oleh karena itu, dalam merencanakan pekerjaan bekisting harus
Indryani, R. (Retno)   +1 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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