Results 81 to 90 of about 18,402,230 (263)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Green High Rise. Low Energy – High Rise Scambio Culturale e Didattico con la Technische Universität München

open access: yes, 2008
Oggetto dello scambio didattico sono state attività di ricerca e di sperimentazione progettuale e tecnologico ambientale sul tema dei green high rise analizzati e progettati con riferimento alla loro sostenibilità ambientale sia come tipologia ...
CANGELLI, Eliana, Dietrich Fink
core  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Finite Element Model Updating Technique for Super High-Rise Building Based on Response Surface Method

open access: yes
To establish a finite element model that accurately represents the dynamic characteristics of actual super high-rise building and improve the accuracy of the finite element simulation results, a finite element model updating method for super high-rise ...
Dongfu Zhao, Hao Li, Yancan Wang
core   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Cost overruns analysis in high rise building and apartment projects

open access: yesTạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kinh tế và Quản trị kinh doanh, 2020
Cost overruns is the lasting problem in construction industry, appears in all over the world. This research was conducted to assess the influence of each factor to the cost overruns in construction projects. The percentage of cost overruns caused by each
Nguyễn Lê Kế Nghiệp   +2 more
doaj  

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Hacia el edificio de renta. La transformación de la vivienda en altura en manos de los arquitectos (Rosario, 1920-1948)

open access: yesDearq, 2012
This article analyses the typological transformations that took place in high-rise accommodation from the 1920’s onwards in Rosario (Argentina). The question that is posed in this paper concerns the role that the architects undertook in the previously ...
Jimena Paula Cutruneo
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

MENGESTIMASI KOEFISIEN BUKAAN Cd PADA JENDELA BANGUNAN TINGGI DENGAN BANTUAN SIMULASI C F D

open access: yesDimensi: Journal of Architecture and Built Environment, 2001
Numerical simulation with CFD (Computational Fluid Dynamic) is actually common method for the researches on building aerodynamics. This study is focused on the observation of air movement behavior through large openings of typical high rise buildings in ...
Suryono Suryono, Sangkertadi Sangkertadi
doaj  

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