Results 31 to 40 of about 1,986,994 (260)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

High Speed Cities

open access: yesTeMA: Journal of Land Use, Mobility and Environment, 2008
Integrazione tra le discipline che studiano le trasformazioni urbane e quelle che affrontano le tematiche del governo della mobilità per la costruzione di un nuovo corpus di conoscenze teorico-metodologiche che, superando gli steccati che segnano il confine – del tutto apparente – tra queste discipline, sia in grado di formulare soluzioni nuove ai ...
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Distributed associative memories for high-speed symbolic reasoning [PDF]

open access: yes, 1996
This paper briefly introduces a novel symbolic reasoning system based upon distributed associative memories which are constructed from correlation matrix memories (CMM). The system is aimed at high-speed rule-based symbolic operations.
Austin, J
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

High speed electro optic polymer micro-ring resonator [PDF]

open access: yes, 2004
An electro-optic polymer micro-ring resonator for high speed modulation was designed, realized and characterized. The design of layer-stack and electrodes was done such that modulation frequencies up till 1 GHz should be possible.
Diemeer, M.B.J.   +2 more
core   +8 more sources

High speed multi focal plane optical system [PDF]

open access: yes, 1983
An apparatus for eliminating beamsplitter generated optical aberrations in a pupil concentric optical system providing a plurality of spatially separated images on different focal planes or surfaces is presented.
Minott, P. O.
core   +1 more source

Deep Learning for High Speed Optical Coherence Elastography

open access: yes, 2020
Mechanical properties of tissue provide valuable information for identifying lesions. One approach to obtain quantitative estimates of elastic properties is shear wave elastography with optical coherence elastography (OCE).
Bengs, Marcel   +5 more
core   +1 more source

A quick-retrieval high-speed digital framing camera [PDF]

open access: yes, 1993
A new high-speed digital framing camera is described. The design is built around a rotating polygon mirror that provides a framing rate of 24 000 frames/s. The camera electronics digitizes an image into a 32×104 grid of pixels, where the second dimension
Bellan, P. M., Sato, A. H., Yee, J.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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