Results 61 to 70 of about 696,698 (308)

High-speed optical imaging with sCMOS pixel reassignment

Nature Communications
Fluorescence microscopy has undergone rapid advancements, offering unprecedented visualization of biological events and shedding light on the intricate mechanisms governing living organisms.
Biagio Mandracchia, Corey Zheng, Suraj Rajendran, Wenhao Liu, Parvin Forghani, Chunhui Xu, Shu Jia   +6 more
doaj   +1 more source

The Onset and Early Stages of Dynamic Wetting of Superspreading and Non-Superspreading Trisiloxane Surfactant Solutions on Hydrophobic Surfaces

Colloids and Interfaces
The onset and early stages of dynamic wetting on different hydrophobic surfaces is investigated experimentally for aqueous solutions of two commercial trisiloxane surfacants of similar chemical structure, one of which exhibits superspreading behaviour ...
Volfango Bertola
doaj   +1 more source

High-speed multispectral confocal biomedical imaging [PDF]

Journal of Biomedical Optics, 2014
A new approach for generating high-speed multispectral confocal images has been developed. The central concept is that spectra can be acquired for each pixel in a confocal spatial scan by using a fast spectrometer based on optical fiber delay lines. This approach merges fast spectroscopy with standard spatial scanning to create datacubes in real time ...
Gary E, Carver, Sarah A, Locknar, William A, Morrison, V Krishnan, Ramanujan, Daniel L, Farkas   +4 more
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Low-Cost High-Speed Imaging System for Observing Vocal Fold Vibration in Voice Disorders

, 2012
Purpose: The aim of this study was to establish a method to observe vocal fold vibration using a low-cost high-speed laryngeal imaging system. Procedures: We assembled a high-speed imaging system with a consumer digital camera and a rigid laryngeal ...
Kaneko, Kenichi, Inoue, Masato, Takahashi, Haruo, Sakaguchi, Koichi   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The effect of using patient-specific guides for total knee replacement without hardware removal in complex post-traumatic arthritis: an in-vitro study

BioMedical Engineering OnLine
Background Post-traumatic knee replacement (PTKR) is frequently complicated by the presence of retained metallic hardware around the joint, which limits the use of intramedullary alignment guides.
Chi-Pin Hsu, Chun-Chieh Chen, Yi-Sheng Chan, Chen-Te Wu, Jeng-Ywan Jeng, Alvin Chao-Yu Chen   +5 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Vortex-electromagnetic-wave-based ISAR imaging for high-speed maneuvering targets

Scientific Reports, 2022
Vortex electromagnetic wave (VEMW) carrying orbital angular momentum (OAM), which is expected to introduce additional degrees of freedom in inverse synthetic aperture radar(ISAR) imaging.
Lijun Bu, Yongzhong Zhu, Yijun Chen, Yufei Yang, Yadan Zang   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source