Results 111 to 120 of about 16,059,891 (259)

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Flow Field Simulation for High Speed Train Gearbox

open access: yes机车电传动, 2017
Regarding the gearbox of a certain type high speed train as the research object, the simulation and analysis of the complex internal flow field during its normal operation was carried out. Three-dimensional model of the gearbox oil lubrication was built,
YANG Zhongkun   +3 more
doaj  

Field acoustic measurements of high-speed train sound along BTIR

open access: yes, 2013
In this paper, single-point field measurements of noise radiated from high-speed trains were performed at two sites along Beijing-Tianjin intercity railway (BTIR), aiming at acquiring the realistic acoustic data for validation and verification of ...
Yu HH(喻华华)   +2 more
core   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Primary study of aerodynamic performance evaluation and optimization of the high-speed train

open access: yes, 2011
With the train speed becoming faster and faster, the aerodynamic drag turns to be one of the essential factor that restricts the train speed ascent. However, no public literature, home or abroad, has dealt with the flow field and aerodynamic performance ...
Hu SC(胡守超)   +5 more
core   +1 more source

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