Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Aerodynamic Optimization of High-Speed Trains Nose using a Genetic Algorithm and Artificial Neural Network [PDF]
, 2011 An aerodynamic optimization of the train aerodynamic characteristics in term of front wind action sensitivity is carried out in this paper. In particular, a genetic algorithm (GA) is used to perform a shape optimization study of a high-speed train nose ...
Crespo Martínez, Antonio +2 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Flow Field Simulation for High Speed Train Gearbox
机车电传动, 2017 Regarding the gearbox of a certain type high speed train as the research object, the simulation and analysis of the complex internal flow field during its normal operation was carried out. Three-dimensional model of the gearbox oil lubrication was built,
YANG Zhongkun +3 more
doaj
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
MOD-0A 200 kW wind turbine generator design and analysis report [PDF]
The design, analysis, and initial performance of the MOD-OA 200 kW wind turbine generator at Clayton, NM is documented. The MOD-OA was designed and built to obtain operation and performance data and experience in utility environments.
Anderson, T. S. +6 more
core +1 more source
Bringing World-Class High-Speed Rail to America: Special General Session, 12th Annual Transportation and Infrastructure Summit, MTI S-09-04 [PDF]
, 2010 The 12th Annual Transportation & Infrastructure Summit, held in Irving, Texas on August 11?14, 2009, provided more than 1,100 attendees from 30 states and 13 countries the opportunity to network and interact with elected representatives and influential ...
MTI
core +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Improved RAkEL's Fault Diagnosis Method for High-Speed Train Traction Transformer. [PDF]
Sensors (Basel), 2023 Li M, Zhou X, Qin S, Bin Z, Wang Y.
europepmc +1 more source