Results 101 to 110 of about 21,494,841 (260)
Pathological complete response of locally advanced triple-negative breast cancer: case report
Background. Triple-negative breast cancer is the most aggressive molecular subtype among breast malignancies. Due to the high proliferative activity of tumor cells and the lack of targets for targeted therapy, neoadjuvant chemotherapy plays the main role
V. V. Konstantinova +3 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Using the remote educational technologies in training students for psychology teaching [PDF]
The paper discusses the model of professional training of students for teaching psychology on the basis of remote educational technologies in pedagogical high school.
Seitbattalova, Aigerim
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Aim. To study clinical equivalence of two bisoprolol medications (Concor ® and Bisogamma®) in patients with mild to moderate arterial hypertension (AH). Material and methods. The study included 32 AH patients (15 men, 17 women): 66 % with Stage I, and 34
S. Yu. Martsevich +8 more
doaj
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Drilling sludge generated during well construction for uranium in-situ leaching (ISL) represents a major waste stream requiring sustainable management.
Zhanibek Seitov +6 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
1928 - 1949 St. Patrick's High School Reunion
Dedicated to the students who attended St. Patrick's High School during the years of 1928 - 1949, Lethbridge, Alberta. (July 29,30,31, 1988)pdf1928 to 1949 Reunion — July 29} 30, 31, 1988This memory book is respectfully dedicated to all who attended St ...
St. Patrick's High School
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