Results 171 to 180 of about 124,559,533 (209)

The developmental trajectory and maturation of the Hulunbuir sheep (Ovis aries) microbiome. [PDF]

Anim Microbiome
Yan A, Li X, Cheng J, Cheng Y, Gebeyew K, Tan Z, Kang J, He Z.   +7 more
europepmc   +1 more source

z‐VAD‐FMK triggers macrophage necroptosis during mycobacterial infection via a non‐canonical off‐target mechanism

mLife, EarlyView.
Abstract Macrophages are the predominant cell type infected by Mycobacterium tuberculosis (Mtb) in tuberculosis (TB). Death of Mtb‐infected macrophages promotes tissue pathology and releases Mtb to infect other cells, suggesting that inhibiting the death of Mtb‐infected macrophages could be an adjunctive treatment of TB.
Rong Hu, Pei Li, Jie Han, Jiamin Huang, Guoyi Huang, Xiuju Jiang, Daniel Pfau, Guobao Li, Yi‐Nan Gong, Carl F. Nathan, Li Zhang   +10 more
wiley   +1 more source

Development of Advanced Thermal Barrier Coatings for Energy Conversion

, 1999
Schulz, U., Kaysser, W.A., Peters, M.
core  

Safety, Tolerability, and Gut Microbiota Impact of Sericin-Derived Oligopeptides (SDOs) from Yellow Silk Cocoons in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. [PDF]

Foods
Oo-Puthinan S, Limpeanchob N, Pichitsiri W, Wangteeraprasert A, Trisat K, Chumee S, Sutheerawattananonda M.   +6 more
europepmc   +1 more source

A transition zone enriched WIF1+ basal cell subtype is associated with benign prostatic hyperplasia

The Journal of Pathology, EarlyView.
Abstract The cellular composition and disease susceptibilities of the distinct zones of the human prostate remain incompletely understood. Benign prostatic hyperplasia (BPH) is a common condition that causes widespread morbidity and is nearly exclusively localized to the transition zone (TZ).
Rulin Wang, Qizhi Zheng, Mindy K Graham, Ajay Vaghasia, Jianyong Liu, Jordan Gregg, Tracy Jones, Anuj Gupta, Nicole Castagna, Yan Zhang, Kornel Schuebel, Jennifer Meyers, Alyza Skaist, Dixie Hoyle, Jasmine Kung, Jessica Hicks, Alok Mishra, Yuhan Yang, William G Nelson, Angelo M De Marzo, Srinivasan Yegnasubramanian   +20 more
wiley   +1 more source

Functional Characterization of a Signal Peptide Peptidase in <i>Phaffia rhodozyma</i> Reveals a Potential Role in Protein Stress Response but Not in Activation of the SREBP Ortholog Sre1. [PDF]

Int J Mol Sci
Baeza M, Gómez M, Apariz G, Barahona S, Alcaíno J.   +4 more
europepmc   +1 more source

Emphysema in an 11‐month‐old boy with alpha‐1 antitrypsin deficiency

Pediatric Investigation, EarlyView.
Pediatric development of emphysema in Alpha‐1 Antitrypsin Deficiency (A1ATD) has been rarely described. In this case report, we document an 11‐month boy with A1ATD phenotype PiZZ with basilar centrilobular emphysema, the earliest such documented case.
Irvin Yi, Rachel Williams, Leela Chandrasekar, Saif Al‐Qatarneh   +3 more
wiley   +1 more source

Metagenomic insights into potential PET hydrolases from Antarctic soils and rhizospheres. [PDF]

Front Microbiol
Berríos-Farías V, Guajardo-Leiva S, Gallardo-Cerda J, Galbán-Malagón C, Egas C, Molina-Montenegro MA, Castro-Nallar E.   +6 more
europepmc   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

PROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima, Wilson Dias Segura, Leonardo Brogliato de Moraes, Reinaldo Souza Oliveira, Pedro Henrique Corteletti Manfio, Alison Felipe Alencar Chaves, Wagner Luiz Batista   +6 more
wiley   +1 more source

PKA-Mediated Proteasome Activation Protects Against Cardiac Remodeling and Heart Failure During Systolic Overload. [PDF]

FASEB J
Ahammed MS, Wu P, Wang Y, Yang L, Sternburg JO, Li F, Liu J, Wang X.   +7 more
europepmc   +1 more source