Results 181 to 190 of about 124,559,533 (209)

Top‐Down CSF Peptidomics Reveals Disease‐Associated Peptide Signatures and Oxidative Modifications in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder

PROTEOMICS, EarlyView.
ABSTRACT Multiple sclerosis and neuromyelitis optica spectrum disorder (NMOSD) are inflammatory demyelinating diseases of the CNS whose diagnosis is mainly based on clinical evidence, magnetic resonance imaging, and the analysis of cerebrospinal fluid (CSF). Current approaches provide only partial insight into disease‐related biological processes, thus
Cristina Contini, Lorena Lorefice, Greca Lai, Alessandra Schirru, Giorgia Zodio, Tiziana Cabras, Alessandra Olianas, Giacomo Diaz, Eleonora Cocco, Barbara Manconi   +9 more
wiley   +1 more source

Heterogeneous blood-brain barrier dysfunction in cerebral small vessel diseases. [PDF]

Alzheimers Dement
Ying Y, Li Y, Yao T, Shao X, Tang W, Montagne A, Chabriat H, Wang DJJ, Wang C, Yang Q, Cheng X.   +10 more
europepmc   +1 more source

Gene turnover in the common ancestor of all C4 grasses

PLANTS, PEOPLE, PLANET, EarlyView.
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira, Ahmed S. Alenazi, Sahr Mian, Ilia J. Leitch, Pascal‐Antoine Christin, Colin P. Osborne, Luke T. Dunning   +6 more
wiley   +1 more source

Meta-analysis of RNA-Seq datasets allows a better understanding of P. tricornutum cellular biology, a requirement to improve the production of Biologics. [PDF]

Sci Rep
Boulogne I, Toustou C, Bardor M.
europepmc   +1 more source

Unravelling Extremophilic Microbiome Diversity and Functional Dynamics in Hypersaline Environment. [PDF]

Microb Ecol
Joseph S, Abraham LS, Premachandran K, Samrot AV, Thirugnanasambandam R, Ragavendhar K, Alodaini HA, Moubayed NM, Hatamleh AA, Mani RR, Chang SW, Ravindran B.   +11 more
europepmc   +1 more source

FlgJ cell-wall hydrolyzing activity enhances, but is not required, for flagellum assembly in <i>Salmonella enterica</i>. [PDF]

J Bacteriol
Chevance YHU, Kinoshita M, Chevance FFV, Minamino T, Namba K, Hughes KT.   +5 more
europepmc   +1 more source

The type II secretion system utilizes GspN for transport of lipoproteins to the <i>Acinetobacter baumannii</i> cell surface. [PDF]

mBio
Roberts CS, Gura C, Sandkvist M.
europepmc   +1 more source

Hybrid Whole-Genome Sequencing of <i>Penicillium crustosum</i> CTM10622 Uncovers a Highly Thermostable Alkaline Serine Lipase with Biotechnological Relevance. [PDF]

Int J Mol Sci
Mechri S, Najjari A, Croze S, Frikha F, Zarai N, Ouzari HI, Noiriel A, Öner ET, Abousalham A, Roes-Hill ML, Tounsi S, Lachuer J, Jaouadi B.   +12 more
europepmc   +1 more source

Unlocking the Dynamics of Human SPPL2a: First Atomistic Characterization of an Alzheimer's-Linked Intramembrane Protease. [PDF]

J Chem Inf Model
Dutta S, Singh MK, Dehury B.
europepmc   +1 more source

Ex vivo maturation of the malaria parasite egress protease SERA6 aids pathway dissection and inhibitor development

Withers-Martinez C, Taha Z, Collins CR, Hackett F, Tan MS, Soudy C, Joshi D, Redmond J, Davies B, Maslen S, Skehel M, George R, Kjaer S, Blackman MJ.   +13 more
europepmc   +1 more source