Many proteins undergo important post-translational proteolytic processing to remove targeting signals and activation peptides, and most proteins undergo proteolytic inactivation and catabolism.
Neil D. Rawlings, Alan J. Barrett
core +1 more source
Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway [PDF]
Objective. Erythropoietin (EPO) is a key regulator of erythropoiesis, playing a role in both the proliferation and differentiation of erythroid cells.
Eggen, BJL +8 more
core +1 more source
Molecular characterisation of recombinant human pyroglutamyl peptidase (type I) [PDF]
Pyroglutamyl Peptidase I (PAP1, EC 3.4.19.3) hydrolytically cleaves pyroglutamic acid (pGlu) from the N-terminal of most pGlu-peptides. In higher organisms Thyrothropin Releasing Hormone is a notable biologically active substrate of PAP1. The sequence of
Vaas, Paul-Roman
core +2 more sources
Characteristics of intracellular peptidase and proteinase activities from the mycelium of a cord-forming wood decay fungus Serpula lacrymans [PDF]
Serpula lacrymans is a basidiomycete cord-forming wood decay fungus which reallocates nitrogen within an extensive perennial mycelial system in response to spatial discontinuities in external nutrient supply.
Burton, Kerry S. +2 more
core +1 more source
'Campylobacter jejuni' gene cj0511 encodes a serine peptidase essential for colonisation [PDF]
According to MEROPS peptidase database, Campylobacter species encode 64 predicted peptidases. However, proteolytic properties of only a few of these proteins have been confirmed experimentally.
Karlyshev, AV +15 more
core +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Interdependence of kallikrein-related peptidases in proteolytic networks [PDF]
Human kallikrein-related peptidases (KLKs) are 15 homologous serine proteases involved in several (patho)physiological processes, including cancer. Secreted as precursors, they are activated upon proteolytic release of a short propeptide. We searched for
Burkhart, Julia M. +28 more
core +1 more source
The development of a combustion temperature standard for the calibration of optical diagnostic techniques [PDF]
This thesis describes the development and evaluation of a high-temperature combustion standard. This comprises a McKenna burner premixed flame, together with a full assessment of its temperature, stability and reproducibility.
Sutton, Gavin
core +6 more sources
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Evaluation of E-waste processing through secondary copper smelting [PDF]
This presentation will report the processing of e-waste and extraction of the valuable metals through secondary copper smelting route (black copper smelting), as shown in Figure 1. The rationale for choosing the selected route will be explained.
Reuter, Markus +9 more
core +1 more source

