Results 241 to 250 of about 16,254,290 (323)

Drought Response and Genetic Variation in Scots Pine Seedlings' Provenances: Insights From High-Throughput Phenotyping for Climate-Resilient Forestry. [PDF]

Evol Appl
Neuwirthová E, Stejskal J, Lhotáková Z, Korecký J, Čepl J, Nikodem A, Panzarová K, Albrechtová J, Lstibůrek M.   +8 more
europepmc   +1 more source

Hierarchical Flux‐Protection Engineering Stabilizes Oxidation‐Prone Metabolic Nodes for High‐Level Curcumin Biosynthesis

Advanced Science, EarlyView.
Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen, Qihang Chen, Shurong Zhang, Yajuan Su, Xiaoyi Zou, Ke Wang, Shike Liu, Qian He, Liang Zhang, Weizhu Zeng, Jingwen Zhou   +10 more
wiley   +1 more source

Integrating Dense Genotyping with High-Throughput Phenotyping Empowers the Genetic Dissection of Berry Quality and Resilience Traits in Grapevine. [PDF]

Adv Sci (Weinh)
Zhang Y, Wang Y, Henke M, Carbonell-Bejerano P, Wang Z, Bert PF, Wang Y, Li H, Kong J, Fan P, Dai Z, Liang Z.   +11 more
europepmc   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

Near-infrared spectroscopy as a high-throughput phenotyping method for fusiform rust resistance in loblolly pine. [PDF]

Plant Phenomics
Lim-Hing S, Conrad AO, Montes CR, Gandhi KJK, Payn KG, Walker TD, Villari C.   +6 more
europepmc   +1 more source

Engineered Transformer Base Editor with Enhanced Editing Efficiency

Advanced Science, EarlyView.
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen, Letong Liang, Rui Xu, Tianyi Wang, Hongyan Chen, Daru Lu   +5 more
wiley   +1 more source

3D reconstruction enables high-throughput phenotyping and quantitative genetic analysis of phyllotaxy. [PDF]

Plant Phenomics
Davis JM, Gaillard M, Tross MC, Shrestha N, Ostermann I, Grove RJ, Li B, Benes B, Schnable JC.   +8 more
europepmc   +1 more source

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

Advanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu, Jiaheng Lin, Yifei Zhu, Ying Liu, Guoren Zhou   +4 more
wiley   +1 more source

High-Throughput Phenotyping for Agronomic Traits in Cassava Using Aerial Imaging. [PDF]

Plants (Basel)
Nascimento JHB, Cortes DFM, Andrade LRB, Gallis RBA, Barbosa RL, Oliveira EJ.   +5 more
europepmc   +1 more source