Results 161 to 170 of about 1,036,014 (384)

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Asymmetric multiplex‐polymerase chain reaction – a high throughput method for detection and sequencing genomic fusion sites in t(4;11) [PDF]

, 2003
Markus Metzler, Ursula Brehm, Thorsten Langer, Susanne Viehmann, Arndt Borkhardt, Martin Stanulla, Martin Schrappe, Jochen Harbott, J. Beck, Wolfgang Rascher, Reinald Repp   +10 more
openalex   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Fast, affordable high-throughput genotyping. On your sequencing platform [PDF]

, 2004

openalex   +1 more source

Direct Electron Detection Electron Energy‐Loss Spectroscopy: Speeding Up 2D Analytical In Situ Transmission Electron Microscopy for Aluminum Alloys

Advanced Engineering Materials, EarlyView.
Scanning transmission electron microscopy imaging techniques are an essential tool to document dynamic developments, such as precipitation in aluminum alloys, during in situ heating experiments using transmission electron microscopy. However, in many cases, chemical information is required to interpret complex nanoscale processes.
Evelin Fisslthaler, Martina Dienstleder, Judith Lammer, Moritz Theissing, Daniel Knez   +4 more
wiley   +1 more source

Bioinformatics methods for high-throughput DNA sequencing data

大数据, 2016
DNA sequence data generated by high-throughput sequencing technology is short in length, and the amount of data is enormous. The challenges and opportunities of the big data in high-throughput sequencing environment were analyzed.
xiaojuan Zhan, dengju Yao, huaiqiu Zhu
doaj  

Fast, flexible high-throughput genotyping. On your sequencing platform. [PDF]

, 2004

openalex   +1 more source

Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells

Cell, 2020
Yunlong Cao, B. Su, Xianghua Guo, Wenjie Sun, Yongqiang Deng, L. Bao, Qinyu Zhu, Xu Zhang, Yinghui Zheng, Chenyan Geng, Xiaoran Chai, Runsheng He, Xiaofeng Li, Qi Lv, Hua Zhu, Wei Deng, Yanfeng Xu, Yanjun Wang, Luxin Qiao, Ya-fang Tan, Liyang Song, Guopeng Wang, Xiaoxia Du, Ning Gao, Jiangning Liu, Junyu Xiao, X. Su, Z. Du, Yingmei Feng, Chuan Qin, C. Qin, R. Jin, X. Xie, CH Vlclvh   +33 more
semanticscholar   +1 more source

Effect of Copper Content on the Microstructure and Mechanical Properties of As‐Cast Refractory MoNbTi Multiprincipal Element Alloys

Advanced Engineering Materials, EarlyView.
Copper addition profoundly impacts MoNbTi multiprincipal element alloys. This study reveals copper's dual role, promoting microstructural refinement and strengthening intermetallics at optimal concentrations. An ideal copper content significantly boosts hardness and compressive strength, achieving superior mechanical performance.
Eder Lopes Ortiz, João Felipe Queiroz Rodrigues, Renato Baldan, Erik Poloni, Giovana da Silva Padilha, Wislei Riuper Osório, Ausdinir Danilo Bortolozo   +6 more
wiley   +1 more source