Rethinking Extracellular Vesicle Signaling
Extracellular vesicles enable cell communication beyond intracellular cargo delivery. This perspective highlights two plausible surface‐based signaling modes: “bind‐and‐stay” and “bind‐and‐leave.” Transient binding to multiple cells challenges the one‐vesicle‐one‐cell model.
Wojciech Chrzanowski, Joy Wolfram
wiley +1 more source
Evaluation of HLA Region-Specific High-Throughput Sequencing FASTQ Reads Combined with Ensemble HLA-Typing Tools for Rapid and High-Confidence HLA Typing. [PDF]
Padul VG +5 more
europepmc +1 more source
Freeform Fabrication of Layered Halide Perovskite Nanowire Heterojunctions
‘All‐at‐once’ freeform fabrication of layered perovskite nanowire heterojunctions is realized by 3D printing employing meniscus‐guided crystallization. The integration of nanoscale additive manufacturing with layered halide perovskites will provide a versatile platform to freely design and realize highly stable perovskite‐based optoelectronic ...
Sixi Cao +8 more
wiley +1 more source
Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease
RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley +1 more source
High-Throughput Sequencing Detects a Viral Complex in <i>Agave Tequilana</i> Plants. [PDF]
Torre-Almaraz R +2 more
europepmc +1 more source
Self‐Regulating Sodium‐Ion Battery Materials: From Phase Reconstruction to Functional Activation
Self‐regulating sodium‐ion batteries hinge on programmable phase behavior in layered oxides, interphases that renew without growth, and electrolytes that steer solvation and chemistry. This review distills mechanisms into design rules that span composition, site and entropy tuning, and self‐buffering anodes, linking operando evidence to choices and ...
Hong Gao +10 more
wiley +1 more source
Editorial: High-throughput sequencing-based investigation of chronic disease markers and mechanisms, volume II. [PDF]
Li H, Cai G, Chen WL, Zhao X, Orlov YL.
europepmc +1 more source
Generative Models for Crystalline Materials
Generative machine learning models are increasingly used in crystalline materials design. This review outlines major generative approaches and assesses their strengths and limitations. It also examines how generative models can be adapted to practical applications, discusses key experimental considerations for evaluating generated structures, and ...
Houssam Metni +15 more
wiley +1 more source
SetBERT: the deep learning platform for contextualized embeddings and explainable predictions from high-throughput sequencing. [PDF]
Ludwig DW +9 more
europepmc +1 more source
Spin‐coated films of the conjugated polymer F8T2 (poly (9,9‐dioctylfluorene‐alt‐bithiophene)) generate superoxide at the film‐medium interface, enabling precise delivery of reactive oxygen species (ROS) as visible‐light “ROS patches.” Coated surfaces drive rapid, localised cytotoxicity in MCF7 cancer monolayers under white light, providing a reagent ...
Joe Kaye +8 more
wiley +1 more source

