Results 31 to 40 of about 22,739,092 (242)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Effect of Tree Quantity and Distribution on the Electric Field under Transmission Lines

open access: yesApplied Sciences
The electric field of transmission lines has serious negative impacts on residents’ production and life with the expansion of high voltage engineering.
Ziyu Wang   +5 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Electric Field Simulations and Analysis for High Voltage High Power Medium Frequency Transformer

open access: yesEnergies, 2017
The electronic power transformer (EPT) raises concerns for its notable size and volume reduction compared with traditional line frequency transformers.
Pei Huang, Chengxiong Mao, Dan Wang
doaj   +1 more source

Space charge dynamics in oil and thick pressboard combined system under polarity reversal voltage [PDF]

open access: yes, 2014
In this study, the space charge dynamics in an oil and oil impregnated pressboard combined insulation system are investigated by the means of pulsed electroacoustic (PEA) technique under voltage polarity reversal conditions. To be closer to the real case
Hao, Miao   +9 more
core   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Simulations of High Non-Uniform Electric Field in Dielectric Barrier Electrode System

open access: yesWalailak Journal of Science and Technology, 2021
An electric field in the dielectric barrier electrode system is necessary for ozone production because ozone is produced by the electric discharge of O2 under a high-intensity electric field.
Pitchasak CHANKUSON, Mudtorlep NISOA
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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