Results 71 to 80 of about 1,864,457 (289)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

The use of high aspect ratio photoresist (SU-8) for super-hydrophobic pattern prototyping [PDF]

open access: yes, 2004
In this work we present a reliable technique for the production of large areas of high aspect-ratio patterns and describe their use as model super-hydrophobic systems.
Carl Evans   +20 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Fabrication Suspended High-Aspect-Ratio Parylene Structures for Large Displacement Requirements

open access: yesInternational Journal of Automation and Smart Technology, 2014
A new method is presented for the fabrication of suspended parylene structures, using dry etching at low temperatures with a single standard silicon wafer.
Wen-Cheng Kuo, Chen-Wei Chen
doaj   +1 more source

Nonaxisymmetric high-aspect-ratio ellipsoids under shear: Lowest-order correction for finite aspect ratios

open access: yesPhysical Review E, 2014
We extend the classic study of the motion of small ellipsoidal particles under shear, focusing on simplifications obtained by considerations of the extreme aspect ratios typical of rheoscopic particles (e.g., Kalliroscope). Specifically, we study conditions under which the long-time behavior of scalene (i.e., triaxial or nonaxisymmetric) ellipsoids are
Feng, Shi, Peter J, Mucha
openaire   +3 more sources

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

High Aspect Ratio Silicon Wire Array Photoelectrochemical Cells [PDF]

open access: yes, 2007
In an effort to develop low-cost solar energy conversion techniques, high uniformity vertically oriented silicon wire arrays have been fabricated.
Atwater, Harry A.   +6 more
core  

High aspect ratio silicon dioxide-coated single-walled carbon nanotube scanning probe nanoelectrodes [PDF]

open access: yes, 2009
We have fabricated high aspect ratio, hydrophilic nanoelectrodes from individual single-walled carbon nanotubes (SWNTs) mounted on conductive atomic force microscope (AFM) tips for use as electrochemical probes.
Ceres, Donato M.   +4 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Aeroelastic Optimization Design for High-Aspect-Ratio Wings with Large Deformation

open access: yesShock and Vibration, 2017
This paper presents a framework of aeroelastic optimization design for high-aspect-ratio wing with large deformation. A highly flexible wing model for wind tunnel test is optimized subjected to multiple aeroelastic constraints.
Changchuan Xie   +3 more
doaj   +1 more source

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