Results 161 to 170 of about 17,674,253 (266)
High Burden of Multidrug-Resistant Bacteria in Eastern Democratic Republic of the Congo: A Retrospective Hospital-Based Study. [PDF]
Kabagale Ansima C +11 more
europepmc +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
High burden of vitamin D deficiency in Chinese university students: impact of sun protection culture. [PDF]
Su S +7 more
europepmc +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Impact of mass distribution on insecticide-treated net coverage and usage in three high burden malaria provinces of Papua New Guinea. [PDF]
Keven JB +15 more
europepmc +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Andersen-Tawil syndrome with high-burden ventricular arrhythmias: a case report. [PDF]
Feng R +6 more
europepmc +1 more source

