Results 81 to 90 of about 343,536 (307)

Educational weight loss interventions in obese and overweight adults with type 2 diabetes : a systematic review and meta‐analysis of randomized controlled trials [PDF]

, 2020
Aim The worldwide prevalence of type 2 diabetes mellitus is increasing, with most individuals with the disease being overweight or obese. Weight loss can reduce disease‐related morbidity and mortality and weight losses of 10–15 kg have been shown to ...
Dhalwani, N., Griffiths, Frances, Kai, J., Kendrick, D., Khunti, K., Maula, A., Weng, S., Woolley, A. K.   +7 more
core   +3 more sources

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

Dietary composition modulates brain mass and solubilizable Aβ levels in a mouse model of aggressive Alzheimer's amyloid pathology

Molecular Neurodegeneration, 2009
Objective Alzheimer's disease (AD) is a progressive neurodegenerative disease of the central nervous system (CNS). Recently, an increased interest in the role diet plays in the pathology of AD has resulted in a focus on the detrimental effects of diets ...
Buxbaum Joseph D, Martins Ralph N, Hyslop Peter, Westaway David, Fraser Paul, Ho Lap, Schmeidler James, Brautigam Hannah, Thomas Carlos, Pedrini Steve, Pasinetti Giulio M, Dickstein Dara L, Hof Patrick R, Ehrlich Michelle E, Gandy Sam   +14 more
doaj   +1 more source

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

Advanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil, Maria Anezaki, Alexandros Simistiras, Stavros Glentis, Nikolaos Scarmeas, Pantelis Hatzis, Konstantinos Rouskas, Antigone S. Dimas   +7 more
wiley   +1 more source

South Beach Diet associated ketoacidosis: a case report

Journal of Medical Case Reports, 2008
Introduction It has been previously unclear whether a "mild" degree of low carbohydrate or "starvation" ketonemia and acidosis induced by a low carbohydrate diet is clinically relevant to a patient. Case presentation A 30-year-old Caucasian male on a low
Chalasani Swapna, Fischer Jacqueline
doaj   +1 more source

Variation in the apparent faecal digestibility of macronutrients and urinary energy excretion for three diets varying in fat and fibre content-- assessment of the Atwater factors and related energy conversion factors : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Nutritional Science at Massey University, Palmerston North, New Zealand [PDF]

, 2007
Background: Current systems to estimate dietary metabolisable energy (ME), often based on Atwater factors, assume that diet ME can be accurately predicted based on a few chemical components and that the ME of components is constant across foods ...
Zou, Maggie Long
core  

Role of gut microbiota in the aetiology of obesity: proposed mechanisms and review of the literature [PDF]

, 2016
The aetiology of obesity has been attributed to several factors (environmental, dietary, lifestyle, host, and genetic factors); however none of these fully explain the increase in the prevalence of obesity worldwide.
Edwards, Christine Ann, Gerasimidis, Konstantinos, Khan, Muhammad Jaffar, Shaikh, M. Guftar   +3 more
core   +3 more sources

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

Advanced Science, EarlyView.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen, Qimeng Wang, Ke Yang, Qinghai Lian, Xuyun Peng, Zhiyong Gong, Xinyi Zhao, Yong Wu, Tian Tao, Siqi Xu, Yifan Chen, Xiaoyan Tang, Jinghui Guo, Geyang Xu, Qi Zhang   +14 more
wiley   +1 more source

Effects of dietary carbohydrate and energy intake on LAT1 protein expression in rat skeletal muscle

Journal of Physical Fitness and Sports Medicine
Glucose has been reported to reduce the expression of L-type amino acid transporter 1 (LAT1) protein in C2C12 myocytes. We therefore hypothesized that increased dietary carbohydrate and energy intake would reduce LAT1 protein expression in rodent ...
Aki Yokogawa, Keigo Tanaka, Ikuru Miura, Shinya Watanabe, Yusuke Iwao, Daisuke Takakura, Tongzhu Zhou, Kohei Kido, Kentaro Kawanaka   +8 more
doaj   +1 more source

Carbohydrate Intake in the Etiology of Crohn's Disease and Ulcerative Colitis [PDF]

, 2014
Background: Diet may have a role in the etiology of inflammatory bowel disease. In previous studies, the associations between increased intakes of carbohydrates, sugar, starch, and inflammatory bowel disease are inconsistent.
Abraham, Amre, Andrew R. Hart, Anja Olsen, Anne Tjonneland, Antoine Racine, Antonia Trichopoulou, Bas Oldenburg, Bennett, Bernstein, Bianchi Porro, Bingham, Bohlscheid-Thomas, Calkins, Chan, Darmon, De Filippo, Domenico Palli, Essebag, Fiona van Schaik, Francesca L. Crowe, Franck Carbonnel, Gaboriau-Routhiau, Geerling, Giovanna Masala, Göran Hallmans, H. Bas Bueno-de-Mesquita, Hart, Heresbach, Hou, Iwaya, Jantchou, Jarnerot, Jostins, Kaaks, Kasper, Katsouyanni, Kay-Tee Khaw, Kim Overvad, Kurakevich, Kurata, Maconi, Manuela M. Bergmann, Margetts, Marie-Christine Boutron-Ruault, Martinez-Medina, Maslowski, Mendall, Moreno-Navarrete, Ocke, Olof Grip, Orholm, Peeters, Persson, Pisani, Pontus Karling, Poullis, Prynne, Quezada, Reif, Riboli, Riboli, Robert Luben, Rosario Tumino, Rudolf Kaaks, Sakamoto, Sartor, Satsangi, Shivananda, Silkoff, Simon S. M. Chan, Slimani, Sonnenberg, Spooren, Stefan Lindgren, Thia, Thornton, Timothy Key, Tjonneland, Tragnone, Turnbaugh, van Liere, Wen, Zhang   +83 more
core   +1 more source