Results 111 to 120 of about 1,454,600 (215)

High-Contrast Imaging of Cholesterol Crystals in Rabbit Arteries Ex Vivo Using LED-Based Polarization Microscopy. [PDF]

Sensors (Basel), 2018
Cho S, Kim K, Kim T, Park H, Kim JM, Lee S, Kang Y, Chang K, Kim C.   +8 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Physics-Informed Artificial Intelligence Design of Picomolar Nanobodies Enables Deep Tumor Penetration and High-Contrast Imaging. [PDF]

Research (Wash D C)
Shi N, Ren C, Zhang L, Wang L, Yang X, Li X, Zhou Y, Wang J, Zhao P, Yao C, Ma Y, Tian J, Huang Q, Xu C, Kuang X, Liu W, Jiang X, Ye J, Gao X, Luo L.   +19 more
europepmc   +1 more source

High-Contrast Imaging of Intermediate-Mass Giants with Long-Term Radial Velocity Trends. [PDF]

Astrophys J, 2016
Ryu T, Sato B, Kuzuhara M, Narita N, Takahashi YH, Uyama T, Kudo T, Kusakabe N, Hashimoto J, Omiya M, Harakawa H, Abe L, Ando H, Brandner W, Brandt TD, Carson JC, Currie T, Egner S, Feldt M, Goto M, Grady CA, Guyon O, Hayano Y, Hayashi M, Hayashi SS, Hełminiak KG, Henning T, Hodapp KW, Ida S, Ishii M, Itoh Y, Iye M, Izumiura H, Janson M, Kambe E, Kandori R, Knapp GR, Kokubo E, Kwon J, Matsuo T, Mayama S, McElwain MW, Mede K, Miyama S, Morino JI, Moro-Martin A, Nishimura T, Pyo TS, Serabyn E, Suenaga T, Suto H, Suzuki R, Takami M, Takato N, Takeda Y, Terada H, Thalmann C, Turner EL, Watanabe M, Wisniewski J, Yamada T, Yoshida M, Takami H, Usuda T, Tamura M.   +64 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Low Angle Ring Illumination Stereomicroscopy (LARIS) Method for High-Contrast Imaging of <i>Drosophila</i> Compound Eyes. [PDF]

Bio Protoc
Biswas J, Kumar A, Singh AK.
europepmc   +1 more source

A new scheme for real-time high-contrast imaging in lung cancer radiotherapy: a proof-of-concept study. [PDF]

Phys Med Biol, 2016
Yan H, Tian Z, Shao Y, Jiang SB, Jia X.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Intermolecular dark resonance energy transfer (DRET) for high contrast imaging of endogenous mRNAs in 3D biological samples. [PDF]

Sci Rep
Barnoin G, De Graeve F, Darnas A, Aicha SB, Monterroso B, Burger A, Besse F, Michel BY.   +7 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source