Results 31 to 40 of about 1,454,600 (215)
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak +9 more
wiley +1 more source
Precision Speckle Pattern Reconstruction for High-contrast Imaging
In high-contrast imaging, a large instrumental, technological, and algorithmic effort is made to reduce residual speckle noise and improve the detection capabilities.
Dotan Gazith, Barak Zackay
doaj +1 more source
High-contrast imaging of Galactic Cepheids with VLT/SPHERE
Context. Classical Cepheids are key distance indicators and benchmarks for stellar evolution, yet most of them are members of binary or multiple systems.
Gallenne A. +12 more
doaj +1 more source
High-contrast and high-resolution X-ray phase-contrast imaging based on betatron sources driven by a laser wakefield accelerator [PDF]
X-ray phase-contrast imaging (XPCI) provides superior sensitivity for the diagnosis of low-Z materials compared with absorption-based techniques. Betatron radiation generated by laser wakefield accelerators, which offers high photon flux, ultra-short ...
Sijie Fan +20 more
doaj +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Real-Time Laser Speckle Imaging of Blood Flow with High Gray Level and High Resolution
Laser speckle contrast imaging (LSCI) is a large measurement ranging, real-time, high spatial resolution optical imaging method. Exisiting reserches show that the low gray level (8-bit) and low resolution (752×480 pixels) camera can effectively monitor ...
ZHANG Zelong, ZHANG Yingchao, WU Bo, DONG Wei, FAN Youben
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source

